High separation efficiency of gold nanomaterials of different aspect ratio and size using capillary transient isotachophoresis.
J Chromatogr A
; 1598: 216-222, 2019 Aug 02.
Article
em En
| MEDLINE
| ID: mdl-30948041
ABSTRACT
Two modes of capillary electrophoresis (CE), capillary zone electrophoresis (CZE) and capillary transient isotachophoresis (ctITP), were compared for the detection and separation of spherical gold nanoparticles (AuNPs) and gold nanorods (AuNRs). The development of ctITP using two different leading ions is described. Overall, when compared to traditional capillary zone electrophoresis (CZE), ctITP resulted in improved peak shape and peak efficiency. Specifically, the number of theoretical plates for AuNR samples increased by a factor of 2-2.5 depending on the choice of leading ion. Further, using ctITP two AuNRs differing by aspect ratio were baseline resolved, whereas the same AuNRs could not be separated using CZE or other techniques like single particle inductively coupled plasma mass spectrometry (spICP-MS) and asymmetric flow field-flow fractionation (AF4). The results of this study demonstrate that ctITP is an efficient on-line technique for the improved detection and separation of gold nanomaterials in CE.
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MEDLINE
Assunto principal:
Técnicas de Química Analítica
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Nanotubos
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Nanopartículas Metálicas
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Isotacoforese
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Ouro
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article