Evaluation of toxicokinetics of nonylphenol in the adult female Sprague-Dawley rats using a physiologically based toxicokinetic model.

Liu, Teng; Cao, Weixin; Di, Qiannan; Zhao, Meng; Xu, Qian

Liu, Teng; Cao, Weixin; Di, Qiannan; Zhao, Meng; Xu, Qian.

Afiliação

Liu T; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.
Cao W; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.
Di Q; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.
Zhao M; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.
Xu Q; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China. Electronic address: q_xu68@163.com.

Regul Toxicol Pharmacol ; 105: 42-50, 2019 Jul.

Article em En | MEDLINE | ID: mdl-30954491

Assuntos

Cromatografia Líquida de Alta Pressão/métodos; Modelos Biológicos; Fenóis/toxicidade; Espectrometria de Massas em Tandem/métodos; Administração Oral; Animais; Calibragem; Feminino; Fenóis/administração & dosagem; Fenóis/farmacocinética; Ratos; Ratos Sprague-Dawley; Distribuição Tecidual; Toxicocinética

Palavras-chave

Nonylphenol; Oral exposure; PBTK; Physiologically based toxicokinetic model; Rats; Risk assessment

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenóis / Cromatografia Líquida de Alta Pressão / Espectrometria de Massas em Tandem / Modelos Biológicos Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google