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A new griseofulvin derivative from a soft coral-derived fungus Eupenicillium sp. SCSIO41208.
Li, Yunqiu; Tan, Yanhong; Liu, Juan; Zhou, Xuefeng; Zeng, Siquan; Dong, Junde; Liu, Yonghong; Yang, Bin.
Afiliação
  • Li Y; School of Pharmacy, Guilin Medical University, Guilin, P. R. China.
  • Tan Y; School of Pharmacy, Guilin Medical University, Guilin, P. R. China.
  • Liu J; Key Laboratory of Marine Bio-resources Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica/Research Center for Marine Microbes, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, P. R. China.
  • Zhou X; Key Laboratory of Marine Bio-resources Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica/Research Center for Marine Microbes, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, P. R. China.
  • Zeng S; Key Laboratory of Marine Bio-resources Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica/Research Center for Marine Microbes, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, P. R. China.
  • Dong J; Key Laboratory of Marine Bio-resources Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica/Research Center for Marine Microbes, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, P. R. China.
  • Liu Y; Key Laboratory of Marine Bio-resources Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica/Research Center for Marine Microbes, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, P. R. China.
  • Yang B; Key Laboratory of Marine Bio-resources Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica/Research Center for Marine Microbes, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, P. R. China.
Nat Prod Res ; 34(20): 2971-2975, 2020 Oct.
Article em En | MEDLINE | ID: mdl-30957549
ABSTRACT
A new griseofulvin derivative, eupenigriseofulvin (1), together with six known compounds, griseofulvin (2), dechlorogriseofluvin (3), dechloroisogriseofulvin (4), trichopyrone (5), 2-(4-hydroxyphenyl)-ethanol (6), and 1-phenylethane-1,2-diol (7), were isolated from the EtOAc extract of Eupenicillium sp. SCSIO41208. The structures of these compounds were elucidated by spectroscopic methods including NMR and mass spectrometry. The absolute configuration of 1 was determined on the basis of electronic circular dichroism (ECD) data analysis.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antozoários / Eupenicillium / Griseofulvina / Antifúngicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antozoários / Eupenicillium / Griseofulvina / Antifúngicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article