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Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants.
Jensen, Sanne Brun; Fahnøe, Ulrik; Pham, Long V; Serre, Stéphanie Brigitte Nelly; Tang, Qi; Ghanem, Lubna; Pedersen, Martin Schou; Ramirez, Santseharay; Humes, Daryl; Pihl, Anne Finne; Filskov, Jonathan; Sølund, Christina Søhoel; Dietz, Julia; Fourati, Slim; Pawlotsky, Jean-Michel; Sarrazin, Christoph; Weis, Nina; Schønning, Kristian; Krarup, Henrik; Bukh, Jens; Gottwein, Judith Margarete.
Afiliação
  • Jensen SB; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Fahnøe U; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Pham LV; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Serre SBN; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Tang Q; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Ghanem L; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Pedersen MS; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Ramirez S; Department of Clinical Microbiology, Copenhagen University Hospital, Hvidovre, Denmark.
  • Humes D; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Pihl AF; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Filskov J; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Sølund CS; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Dietz J; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Fourati S; Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
  • Pawlotsky JM; Department of Internal Medicine 1, University Hospital Frankfurt, and German Center for Infection Research, External Partner Site, Frankfurt, Germany.
  • Sarrazin C; National Reference Center for Viral Hepatitis B, C and D, Department of Virology, Henri Mondor Hospital, University of Paris-Est, and INSERM U955, Créteil, France.
  • Weis N; National Reference Center for Viral Hepatitis B, C and D, Department of Virology, Henri Mondor Hospital, University of Paris-Est, and INSERM U955, Créteil, France.
  • Schønning K; Department of Internal Medicine 1, University Hospital Frankfurt, and German Center for Infection Research, External Partner Site, Frankfurt, Germany.
  • Krarup H; Medizinische Klinik II, St. Josefs-Hospital, Wiesbaden, Germany.
  • Bukh J; Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
  • Gottwein JM; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Hepatology ; 70(3): 771-787, 2019 09.
Article em En | MEDLINE | ID: mdl-30964552

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Inibidores de Proteases / Hepatite C Crônica / Farmacorresistência Viral Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Inibidores de Proteases / Hepatite C Crônica / Farmacorresistência Viral Idioma: En Ano de publicação: 2019 Tipo de documento: Article