BTV antibody longevity in cattle five to eight years post BTV-8 vaccination.
Vaccine
; 37(20): 2656-2660, 2019 05 06.
Article
em En
| MEDLINE
| ID: mdl-30979569
ABSTRACT
The Bluetongue virus serotype -8 (BTV-8) epizootic in Germany (2006-2008) was successfully eradicated, essentially by the massive application of commercially available inactivated BTV-8 vaccines. While a six-year antibody longevity of BTV antibodies post BTV-8 vaccination in cattle has been described previously, our study investigated the BTV-8-vaccine antibodies in cattle for up to eight years. In total, 157 bovine serum samples were analysed for the presence of group-specific BTV antibodies in both a commercial cELISA, and a BTV-8- specific serum neutralization test. A robust number of cattle were seropositive for group- and serotype-specific neutralising antibodies for five or more years. In selected animals, born and vaccinated in 2009 or later, the presence of BTV antibodies for up to eight years post BTV-8 vaccination could be confirmed. Our data also show, that booster vaccination prolonged the antibody longevity of vaccine-induced antibodies and the number of serologically positive cattle.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Vacinas Virais
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Bluetongue
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Vírus Bluetongue
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Anticorpos Antivirais
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article