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Transcriptome and Proteome Profiling of Neural Induced Pluripotent Stem Cells from Individuals with Down Syndrome Disclose Dynamic Dysregulations of Key Pathways and Cellular Functions.
Sobol, Maria; Klar, Joakim; Laan, Loora; Shahsavani, Mansoureh; Schuster, Jens; Annerén, Göran; Konzer, Anne; Mi, Jia; Bergquist, Jonas; Nordlund, Jessica; Hoeber, Jan; Huss, Mikael; Falk, Anna; Dahl, Niklas.
Afiliação
  • Sobol M; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Box 815, SE-751 08, Uppsala, Sweden.
  • Klar J; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Box 815, SE-751 08, Uppsala, Sweden.
  • Laan L; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Box 815, SE-751 08, Uppsala, Sweden.
  • Shahsavani M; Department of Neuroscience, Karolinska Institutet Solna, SE-171 65, Stockholm, Sweden.
  • Schuster J; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Box 815, SE-751 08, Uppsala, Sweden.
  • Annerén G; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Box 815, SE-751 08, Uppsala, Sweden.
  • Konzer A; Department of Chemistry - BMC, Analytical Chemistry, Uppsala University, Box 599, SE-751 24, Uppsala, Sweden.
  • Mi J; Department of Chemistry - BMC, Analytical Chemistry, Uppsala University, Box 599, SE-751 24, Uppsala, Sweden.
  • Bergquist J; Department of Chemistry - BMC, Analytical Chemistry, Uppsala University, Box 599, SE-751 24, Uppsala, Sweden.
  • Nordlund J; Department of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, SE-751 44, Uppsala, Sweden.
  • Hoeber J; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Box 815, SE-751 08, Uppsala, Sweden.
  • Huss M; Department of Biochemistry and Biophysics, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Stockholm University, Box 1031, SE-171 21, Solna, Sweden.
  • Falk A; Department of Neuroscience, Karolinska Institutet Solna, SE-171 65, Stockholm, Sweden.
  • Dahl N; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Box 815, SE-751 08, Uppsala, Sweden. niklas.dahl@igp.uu.se.
Mol Neurobiol ; 56(10): 7113-7127, 2019 Oct.
Article em En | MEDLINE | ID: mdl-30989628
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome de Down / Proteoma / Células-Tronco Pluripotentes Induzidas / Transcriptoma / Neurônios Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome de Down / Proteoma / Células-Tronco Pluripotentes Induzidas / Transcriptoma / Neurônios Idioma: En Ano de publicação: 2019 Tipo de documento: Article