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Exploitation of Antibiotic Resistance as a Novel Drug Target: Development of a ß-Lactamase-Activated Antibacterial Prodrug.
Evans, Lindsay E; Krishna, Aishwarya; Ma, Yajing; Webb, Thomas E; Marshall, Dominic C; Tooke, Catherine L; Spencer, James; Clarke, Thomas B; Armstrong, Alan; Edwards, Andrew M.
Afiliação
  • Evans LE; MRC Centre for Molecular Bacteriology and Infection , Imperial College London , SW7 2AZ London , United Kingdom.
  • Krishna A; Department of Chemistry, Molecular Sciences Research Hub , Imperial College London , W12 0BZ London , United Kingdom.
  • Ma Y; MRC Centre for Molecular Bacteriology and Infection , Imperial College London , SW7 2AZ London , United Kingdom.
  • Webb TE; Department of Chemistry, Molecular Sciences Research Hub , Imperial College London , W12 0BZ London , United Kingdom.
  • Marshall DC; Department of Medicine , Imperial College London , SW7 2AZ London , United Kingdom.
  • Tooke CL; Department of Medicine , Imperial College London , SW7 2AZ London , United Kingdom.
  • Spencer J; School of Cellular and Molecular Medicine , University of Bristol , Biomedical Sciences Building, University Walk , BS8 1TD Bristol , United Kingdom.
  • Clarke TB; School of Cellular and Molecular Medicine , University of Bristol , Biomedical Sciences Building, University Walk , BS8 1TD Bristol , United Kingdom.
  • Armstrong A; MRC Centre for Molecular Bacteriology and Infection , Imperial College London , SW7 2AZ London , United Kingdom.
  • Edwards AM; Department of Chemistry, Molecular Sciences Research Hub , Imperial College London , W12 0BZ London , United Kingdom.
J Med Chem ; 62(9): 4411-4425, 2019 05 09.
Article em En | MEDLINE | ID: mdl-31009558
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Beta-Lactamases / Pró-Fármacos / Ciprofloxacina / Cefalosporinas / Antibacterianos Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Beta-Lactamases / Pró-Fármacos / Ciprofloxacina / Cefalosporinas / Antibacterianos Idioma: En Ano de publicação: 2019 Tipo de documento: Article