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A phase 1 trial of the oral DNA methyltransferase inhibitor CC-486 and the histone deacetylase inhibitor romidepsin in advanced solid tumors.
Gaillard, Stéphanie L; Zahurak, Marianna; Sharma, Anup; Durham, Jennifer N; Reiss, Kim A; Sartorius-Mergenthaler, Susan; Downs, Melinda; Anders, Nicole M; Ahuja, Nita; Rudek, Michelle A; Azad, Nilofer.
Afiliação
  • Gaillard SL; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland.
  • Zahurak M; Department of Gynecology and Obstetrics, Division of Gynecologic Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland.
  • Sharma A; Department of Oncology, Division of Biostatistics and Bioinformatics, Johns Hopkins School of Medicine, Baltimore, Maryland.
  • Durham JN; Department of Surgery, Division of Surgical Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland.
  • Reiss KA; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland.
  • Sartorius-Mergenthaler S; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland.
  • Downs M; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland.
  • Anders NM; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland.
  • Ahuja N; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland.
  • Rudek MA; Department of Surgery, Division of Surgical Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland.
  • Azad N; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland.
Cancer ; 125(16): 2837-2845, 2019 08 15.
Article em En | MEDLINE | ID: mdl-31012962
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Metilases de Modificação do DNA / Protocolos de Quimioterapia Combinada Antineoplásica / Depsipeptídeos / Inibidores de Histona Desacetilases / Neoplasias Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Metilases de Modificação do DNA / Protocolos de Quimioterapia Combinada Antineoplásica / Depsipeptídeos / Inibidores de Histona Desacetilases / Neoplasias Idioma: En Ano de publicação: 2019 Tipo de documento: Article