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PARP Inhibitor Efficacy Depends on CD8+ T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer.
Pantelidou, Constantia; Sonzogni, Olmo; De Oliveria Taveira, Mateus; Mehta, Anita K; Kothari, Aditi; Wang, Dan; Visal, Tanvi; Li, Michelle K; Pinto, Jocelin; Castrillon, Jessica A; Cheney, Emily M; Bouwman, Peter; Jonkers, Jos; Rottenberg, Sven; Guerriero, Jennifer L; Wulf, Gerburg M; Shapiro, Geoffrey I.
Afiliação
  • Pantelidou C; Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, Massachusetts.
  • Sonzogni O; Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
  • De Oliveria Taveira M; Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
  • Mehta AK; Department of Imaging, A.C. Camargo Cancer Center, São Paulo, Brazil.
  • Kothari A; Breast Tumor Immunology Laboratory, Susan F. Smith Center for Women's Cancers, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Wang D; Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, Massachusetts.
  • Visal T; Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
  • Li MK; Otorhinolaryngology Hospital, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
  • Pinto J; Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, Massachusetts.
  • Castrillon JA; Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
  • Cheney EM; Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
  • Bouwman P; Breast Tumor Immunology Laboratory, Susan F. Smith Center for Women's Cancers, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Jonkers J; Breast Tumor Immunology Laboratory, Susan F. Smith Center for Women's Cancers, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Rottenberg S; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Guerriero JL; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Wulf GM; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Shapiro GI; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Switzerland.
Cancer Discov ; 9(6): 722-737, 2019 06.
Article em En | MEDLINE | ID: mdl-31015319
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Linfócitos T CD8-Positivos / Neoplasias de Mama Triplo Negativas / Proteínas de Membrana Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Linfócitos T CD8-Positivos / Neoplasias de Mama Triplo Negativas / Proteínas de Membrana Idioma: En Ano de publicação: 2019 Tipo de documento: Article