Outcomes and timing of endoscopic retrograde cholangiopancreatography for acute biliary pancreatitis.
Dig Liver Dis
; 51(9): 1281-1286, 2019 09.
Article
em En
| MEDLINE
| ID: mdl-31031177
ABSTRACT
BACKGROUND:
Indication of endoscopic retrograde cholangiopancreatography (ERCP) in acute biliary pancreatitis (ABP) is challenging.AIMS:
In this retrospective study, we analyzed real-world data to understand the ERCP practice in ABP in Hungarian centers.METHODS:
Clinical data on ABP patients (2013-2015) were extracted from our large multicentric database. Outcomes, quality indicators and the role of early timing of ERCP (<24 h from admission) were analyzed.RESULTS:
There were 356 patients with ABP. ERCP was performed in 267 (75%). Performance indicators of ERCP proved to be suboptimal with a biliary cannulation rate of 84%. Successful vs unsuccessful cannulation of naïve papilla resulted in lower rates of local [22.9% vs 40.9%, (P = 0.012)] and systemic [4.9% vs 13.6%, (P = 0.042)] complications. Successful vs unsuccessful clearance resulted in lower rates of local complications [22.5% vs 40.8%, (P = 0.008)]. Successful cannulation and drainage correlated with less severe course of ABP [3.6% vs 15.9%, (P = 0.001) and 4.1% vs 12.2%, (P = 0.033)] respectively. A tendency of an increased rate of local complications was observed if ERCP was performed later [<24 h 21.1% (35/166); between 24-48 h 23.4% (11/47); >48h 37.2% (16/43) (P = 0.088)].CONCLUSION:
Optimization of ERCP indication in ABP patients is critical as suboptimal ERCP practices in ABP without definitive stone detection are associated with poorer clinical outcomes.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Pancreatite
/
Doenças Biliares
/
Colangiopancreatografia Retrógrada Endoscópica
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article