GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells.

Zhang, Beibei; Ayuda-Durán, Pilar; Piechaczyk, Laure; Fløisand, Yngvar; Safont, Mireia Mayoral; Karlsen, Ida Tveit; Fandalyuk, Zina; Tadele, Dagim; van Mierlo, Pepijn; Rowe, Alexander D; Robertson, Joseph M; Gjertsen, Bjørn Tore; McCormack, Emmet; Enserink, Jorrit M.

Afiliação

Zhang B; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Montebello.
Ayuda-Durán P; Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, Montebello.
Piechaczyk L; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Montebello.
Fløisand Y; Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, Montebello.
Safont MM; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Montebello.
Karlsen IT; Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, Montebello.
Fandalyuk Z; Institute of Clinical Medicine, University of Oslo.
Tadele D; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Montebello.
van Mierlo P; Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, Montebello.
Rowe AD; Department of Hematology, Oslo University Hospital, Rikshospitalet, Oslo.
Robertson JM; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen.
Gjertsen BT; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen.
McCormack E; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen.
Enserink JM; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Montebello.

Haematologica ; 104(5): e229, 2019 05.

Article em En | MEDLINE | ID: mdl-31040234

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article