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Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs.
Sperling, Adam S; Burgess, Michael; Keshishian, Hasmik; Gasser, Jessica A; Bhatt, Shruti; Jan, Max; Slabicki, Mikolaj; Sellar, Rob S; Fink, Emma C; Miller, Peter G; Liddicoat, Brian J; Sievers, Quinlan L; Sharma, Rohan; Adams, Dylan N; Olesinski, Elyse A; Fulciniti, Mariateresa; Udeshi, Namrata D; Kuhn, Eric; Letai, Anthony; Munshi, Nikhil C; Carr, Steven A; Ebert, Benjamin L.
Afiliação
  • Sperling AS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Burgess M; Division of Hematology, Brigham and Women's Hospital, Boston, MA.
  • Keshishian H; Broad Institute of MIT and Harvard, Cambridge, MA.
  • Gasser JA; Broad Institute of MIT and Harvard, Cambridge, MA.
  • Bhatt S; Broad Institute of MIT and Harvard, Cambridge, MA.
  • Jan M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Slabicki M; Division of Hematology, Brigham and Women's Hospital, Boston, MA.
  • Sellar RS; Broad Institute of MIT and Harvard, Cambridge, MA.
  • Fink EC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Miller PG; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Liddicoat BJ; Division of Hematology, Brigham and Women's Hospital, Boston, MA.
  • Sievers QL; Broad Institute of MIT and Harvard, Cambridge, MA.
  • Sharma R; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Adams DN; Division of Hematology, Brigham and Women's Hospital, Boston, MA.
  • Olesinski EA; Broad Institute of MIT and Harvard, Cambridge, MA.
  • Fulciniti M; Division of Translational Oncology, National Center for Tumor Diseases Heidelberg, German Cancer Research Center, Heidelberg, Germany; and.
  • Udeshi ND; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Kuhn E; Division of Hematology, Brigham and Women's Hospital, Boston, MA.
  • Letai A; Broad Institute of MIT and Harvard, Cambridge, MA.
  • Munshi NC; Department of Haematology, UCL Cancer Institute, University College London, London, United Kingdom.
  • Carr SA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Ebert BL; Division of Hematology, Brigham and Women's Hospital, Boston, MA.
Blood ; 134(2): 160-170, 2019 07 11.
Article em En | MEDLINE | ID: mdl-31043423
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Talidomida / Ubiquitina-Proteína Ligases / Proteólise Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Talidomida / Ubiquitina-Proteína Ligases / Proteólise Idioma: En Ano de publicação: 2019 Tipo de documento: Article