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Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series.
Fages, Antoine; Hanghøj, Kristian; Khan, Naveed; Gaunitz, Charleen; Seguin-Orlando, Andaine; Leonardi, Michela; McCrory Constantz, Christian; Gamba, Cristina; Al-Rasheid, Khaled A S; Albizuri, Silvia; Alfarhan, Ahmed H; Allentoft, Morten; Alquraishi, Saleh; Anthony, David; Baimukhanov, Nurbol; Barrett, James H; Bayarsaikhan, Jamsranjav; Benecke, Norbert; Bernáldez-Sánchez, Eloísa; Berrocal-Rangel, Luis; Biglari, Fereidoun; Boessenkool, Sanne; Boldgiv, Bazartseren; Brem, Gottfried; Brown, Dorcas; Burger, Joachim; Crubézy, Eric; Daugnora, Linas; Davoudi, Hossein; de Barros Damgaard, Peter; de Los Ángeles de Chorro Y de Villa-Ceballos, María; Deschler-Erb, Sabine; Detry, Cleia; Dill, Nadine; do Mar Oom, Maria; Dohr, Anna; Ellingvåg, Sturla; Erdenebaatar, Diimaajav; Fathi, Homa; Felkel, Sabine; Fernández-Rodríguez, Carlos; García-Viñas, Esteban; Germonpré, Mietje; Granado, José D; Hallsson, Jón H; Hemmer, Helmut; Hofreiter, Michael; Kasparov, Aleksei; Khasanov, Mutalib; Khazaeli, Roya.
Afiliação
  • Fages A; Laboratoire d'Anthropobiologie Moléculaire et d'Imagerie de Synthèse, CNRS UMR 5288, Université de Toulouse, Université Paul Sabatier, 31000 Toulouse, France; Lundbeck Foundation GeoGenetics Center, University of Copenhagen, 1350K Copenhagen, Denmark.
  • Hanghøj K; Laboratoire d'Anthropobiologie Moléculaire et d'Imagerie de Synthèse, CNRS UMR 5288, Université de Toulouse, Université Paul Sabatier, 31000 Toulouse, France; Lundbeck Foundation GeoGenetics Center, University of Copenhagen, 1350K Copenhagen, Denmark.
  • Khan N; Lundbeck Foundation GeoGenetics Center, University of Copenhagen, 1350K Copenhagen, Denmark; Department of Biotechnology, Abdul Wali Khan University, Mardan, Pakistan.
  • Gaunitz C; Lundbeck Foundation GeoGenetics Center, University of Copenhagen, 1350K Copenhagen, Denmark.
  • Seguin-Orlando A; Laboratoire d'Anthropobiologie Moléculaire et d'Imagerie de Synthèse, CNRS UMR 5288, Université de Toulouse, Université Paul Sabatier, 31000 Toulouse, France; Lundbeck Foundation GeoGenetics Center, University of Copenhagen, 1350K Copenhagen, Denmark.
  • Leonardi M; Lundbeck Foundation GeoGenetics Center, University of Copenhagen, 1350K Copenhagen, Denmark; Evolutionary Ecology Group, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK.
  • McCrory Constantz C; Lundbeck Foundation GeoGenetics Center, University of Copenhagen, 1350K Copenhagen, Denmark; Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA 94305, USA.
  • Gamba C; Lundbeck Foundation GeoGenetics Center, University of Copenhagen, 1350K Copenhagen, Denmark.
  • Al-Rasheid KAS; Zoology Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
  • Albizuri S; Seminari d'Estudis i Recerques Prehistoriques, HAR2017-87695-P, Universitat de Barcelona, Barcelona, Spain.
  • Alfarhan AH; Zoology Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
  • Allentoft M; Lundbeck Foundation GeoGenetics Center, University of Copenhagen, 1350K Copenhagen, Denmark.
  • Alquraishi S; Zoology Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
  • Anthony D; Anthropology Department, Hartwick College 1, Oneonta, NY 13820, USA.
  • Baimukhanov N; Shejire DNA project, 050046 Almaty, Kazakhstan.
  • Barrett JH; McDonald Institute for Archaeological Research, Department of Archaeology, University of Cambridge, Cambridge CB2 3ER, UK.
  • Bayarsaikhan J; National Museum of Mongolia, Ulaanbaatar 210646, Mongolia.
  • Benecke N; Deutsches Archäologisches Institut (DAI), 14195 Berlin, Germany.
  • Bernáldez-Sánchez E; Laboratorio de Paleontologia y Paleobiologia, Instituto Andaluz del Patrimonio Historico, Sevilla, Spain.
  • Berrocal-Rangel L; Departamento de Prehistoria y Arqueología, Universidad Autónoma de Madrid, Madrid, Spain.
  • Biglari F; Department of Paleolithic, National Museum of Iran, 1136918111, Tehran, Iran.
  • Boessenkool S; Centre for Ecological and Evolutionary Synthesis (CEES), Department of Biosciences, University of Oslo, Postbox 1066, Blindern, 0316 Oslo, Norway.
  • Boldgiv B; Ecology Group, Department of Biology, School of Arts and Sciences, National University of Mongolia, Ulaanbaatar 14201, Mongolia.
  • Brem G; Institute of Animal Breeding and Genetics, Department of Biomedical Sciences, Veterinary University of Vienna, 1210 Vienna, Austria.
  • Brown D; Anthropology Department, Hartwick College 1, Oneonta, NY 13820, USA.
  • Burger J; Palaeogenetics Group, Institute of Organismic and Molecular Evolution (iOME), Johannes Gutenberg-University Mainz, 55099 Mainz, Germany.
  • Crubézy E; Laboratoire d'Anthropobiologie Moléculaire et d'Imagerie de Synthèse, CNRS UMR 5288, Université de Toulouse, Université Paul Sabatier, 31000 Toulouse, France.
  • Daugnora L; Osteological material research laboratory, Klaipeda university, Klaipeda 92294, Lithuania.
  • Davoudi H; Department of Osteology, National Museum of Iran, 1136918111, Tehran, Iran; Department of Archaeology, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran.
  • de Barros Damgaard P; Lundbeck Foundation GeoGenetics Center, University of Copenhagen, 1350K Copenhagen, Denmark.
  • de Los Ángeles de Chorro Y de Villa-Ceballos M; Centro de Biología Molecular Severo Ochoa (CSIC-UAM), E-28049, Madrid, Spain.
  • Deschler-Erb S; Integrative prähistorische und naturwissenschaftliche Archäologie (IPNA), 4055 Basel, Switzerland.
  • Detry C; Uniarq, Centro de Arqueologia da Universidade de Lisboa, Faculdade de Letras da Universidade de Lisboa, 1600-214 Lisboa, Portugal.
  • Dill N; Integrative prähistorische und naturwissenschaftliche Archäologie (IPNA), 4055 Basel, Switzerland.
  • do Mar Oom M; CE3C-Centre for Ecology, Evolution and Environmental Changes, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.
  • Dohr A; Institute for Pre- and Protohistoric Archaeology and Archaeology of the Roman Provinces, Ludwig-Maximilians-University Munich, 80539 München, Germany; ArchaeoBioCenter, Ludwig-Maximilians-University Munich, 80539 München, Germany; Institute of Palaeoanatomy, Domestication Research and History of Vet
  • Ellingvåg S; Explico Foundation, 6900 Florø, Norway.
  • Erdenebaatar D; Department of Archaeology, Ulaanbaatar State University, Ulaanbaatar 51, Mongolia.
  • Fathi H; Department of Osteology, National Museum of Iran, 1136918111, Tehran, Iran; Archaezoology section, Bioarchaeology Laboratory of the Central Laboratory, University of Tehran, Tehran CP1417634934, Iran.
  • Felkel S; Institute of Animal Breeding and Genetics, Department of Biomedical Sciences, Veterinary University of Vienna, 1210 Vienna, Austria.
  • Fernández-Rodríguez C; Departamento de Historia, Facultad de Filosofía y Letras, Universidad de León, León, Spain.
  • García-Viñas E; Departamento de Sistemas Físicos, Químicos y Naturales, Universidad Pablo de Olavide, 41013 Sevilla, Spain.
  • Germonpré M; Operational Direction, Earth and History of Life, Royal Belgian Institute of Natural Sciences, 1000, Brussels, Belgium.
  • Granado JD; Integrative prähistorische und naturwissenschaftliche Archäologie (IPNA), 4055 Basel, Switzerland.
  • Hallsson JH; Faculty of Agricultural and Environmental Sciences, The Agricultural University of Iceland, Keldnaholti - Árleyni 22, 112 Reykjavík, Iceland.
  • Hemmer H; Palaeogenetics Group, Institute of Organismic and Molecular Evolution (iOME), Johannes Gutenberg-University Mainz, 55099 Mainz, Germany.
  • Hofreiter M; University of Potsdam, Faculty of Mathematics and Natural Sciences, Institute for Biochemistry and Biology, 14476 Potsdam, Germany.
  • Kasparov A; Institute for the History of Material Culture, Russian Academy of Sciences, St. Petersburg 191186, Russia.
  • Khasanov M; Archaeology Institute of Samarkand, Uzbekistan.
  • Khazaeli R; Department of Osteology, National Museum of Iran, 1136918111, Tehran, Iran; Archaezoology section, Bioarchaeology Laboratory of the Central Laboratory, University of Tehran, Tehran CP1417634934, Iran.
Cell ; 177(6): 1419-1435.e31, 2019 05 30.
Article em En | MEDLINE | ID: mdl-31056281
ABSTRACT
Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time series for a non-human organism to date, including genome-scale data from 149 ancient animals and 129 ancient genomes (≥1-fold coverage), 87 of which are new. This extensive dataset allows us to assess the modern legacy of past equestrian civilizations. We find that two extinct horse lineages existed during early domestication, one at the far western (Iberia) and the other at the far eastern range (Siberia) of Eurasia. None of these contributed significantly to modern diversity. We show that the influence of Persian-related horse lineages increased following the Islamic conquests in Europe and Asia. Multiple alleles associated with elite-racing, including at the MSTN "speed gene," only rose in popularity within the last millennium. Finally, the development of modern breeding impacted genetic diversity more dramatically than the previous millennia of human management.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cavalos Idioma: En Ano de publicação: 2019 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cavalos Idioma: En Ano de publicação: 2019 Tipo de documento: Article