Rhodium(III)-Catalyzed Intramolecular Annulations of Acrylic and Benzoic Acids to Alkynes.
ACS Omega
; 4(4): 6257-6263, 2019 Apr 30.
Article
em En
| MEDLINE
| ID: mdl-31058249
ABSTRACT
Rh(III) catalysts can promote a formal (4 + 2) intramolecular oxidative annulation between acrylic or benzoic acid derivatives and alkynes. The reaction, which involves a C-H activation process, allows for a rapid assembly of appealing bicyclic pyran-2-ones and tricyclic isocoumarin derivatives in moderate to good yields. The α-pyrone moiety of the products provides for further manipulations to obtain relatively complex cyclic skeletons in a very simple manner.
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MEDLINE
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En
Ano de publicação:
2019
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Article