Potential use of Pichia pastoris strain SMD1168H expressing DNA topoisomerase I in the screening of potential anti­breast cancer agents.

Xin, Jian; Wan Mahtar, Wan Nor Azlin; Siah, Poh Chiew; Miswan, Noorizan; Khoo, Boon Yin

Potential use of Pichia pastoris strain SMD1168H expressing DNA topoisomerase I in the screening of potential antibreast cancer agents.

Xin, Jian; Wan Mahtar, Wan Nor Azlin; Siah, Poh Chiew; Miswan, Noorizan; Khoo, Boon Yin.

Afiliação

Xin J; Department of General Surgery, Taizhou First People's Hospital in Zhejiang Province, Taizhou, Zhejiang 318020, P.R. China.
Wan Mahtar WNA; Department of Microbiology, School of Biological Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia.
Siah PC; Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 Penang, Malaysia.
Miswan N; Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 Penang, Malaysia.
Khoo BY; Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 Penang, Malaysia.

Mol Med Rep ; 19(6): 5368-5376, 2019 Jun.

Article em En | MEDLINE | ID: mdl-31059050

Assuntos

Antineoplásicos Fitogênicos/farmacologia; DNA Topoisomerases Tipo I/metabolismo; Pichia/efeitos dos fármacos; Camptotecina/farmacologia; Linhagem Celular Tumoral; Sobrevivência Celular/efeitos dos fármacos; DNA Topoisomerases Tipo I/genética; Ácido Glutâmico/farmacologia; Humanos; Pichia/metabolismo; Proteínas Recombinantes/biossíntese; Proteínas Recombinantes/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pichia / DNA Topoisomerases Tipo I / Antineoplásicos Fitogênicos Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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