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The emerging role of trans-oral robotic surgery for the detection of the primary tumour site in patients with head-neck unknown primary cancers: A meta-analysis.
Meccariello, Giuseppe; Cammaroto, Giovanni; Ofo, Enyinnaya; Calpona, Sebastiano; Parisi, Elisabetta; D'Agostino, Giovanni; Gobbi, Riccardo; Firinu, Elisabetta; Bellini, Chiara; De Vito, Andrea; Montevecchi, Filippo; Costantini, Matteo; Amadori, Elena; Nuzzo, Simona; Pelucchi, Stefano; Vicini, Claudio.
Afiliação
  • Meccariello G; Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Azienda USL della Romagna, Forlì, Italy. Electronic address: drmeccariello@gmail.com.
  • Cammaroto G; Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Azienda USL della Romagna, Forlì, Italy; Department of Otolaryngology and Head-Neck Surgery, University of Messina, Italy.
  • Ofo E; St George's University Hospital, Kingston Hospital NHS Foundation Trusts, London, UK.
  • Calpona S; Osteoncology and Rare Tumors Center, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori(IRST), IRCCS, Meldola, Italy.
  • Parisi E; Radiotherapy Department, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori(IRST), IRCCS, Meldola, Italy.
  • D'Agostino G; Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Azienda USL della Romagna, Forlì, Italy.
  • Gobbi R; Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Azienda USL della Romagna, Forlì, Italy.
  • Firinu E; Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Azienda USL della Romagna, Forlì, Italy.
  • Bellini C; Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Azienda USL della Romagna, Forlì, Italy.
  • De Vito A; Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Azienda USL della Romagna, Forlì, Italy.
  • Montevecchi F; Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Azienda USL della Romagna, Forlì, Italy.
  • Costantini M; Department of Surgical Pathology, Morgagni Pierantoni Hospital, Azienda USL della Romagna, Forlì, Italy.
  • Amadori E; Radiology Department, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori(IRST), IRCCS, Meldola, Italy.
  • Nuzzo S; Department of Biostatistics, Azienda USL della Romagna, Forlì, Italy.
  • Pelucchi S; ENT Department, University Hospital of Ferrara, Italy.
  • Vicini C; Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Azienda USL della Romagna, Forlì, Italy.
Auris Nasus Larynx ; 46(5): 663-671, 2019 Oct.
Article em En | MEDLINE | ID: mdl-31064689
ABSTRACT
The identification of the site in head neck unknown primary (HNUP) tumour is of utmost importance to help select best treatment while decreasing treatment-related morbidity and mortality. The primary purpose of this study is to demonstrate that TORS may be a valuable tool in detecting primary tumour. Studies were systematically searched in the PubMed, EMBASE, the Cochrane Library and CENTRAL electronic databases. A total of 12 selected studies (349 patients) were analyzed. The primary tumour detection and positive surgical margins rates were 70.8% and 19.4%, respectively. The rate of HPV-related tumour was 71.3%. The primary tumour was mainly in base of tongue (64%). In conclusion, TORS seems to be an effective surgical approach both in terms of detection of primary tumour site and in terms of therapeutic perspective for HNUP. In particular, a subset of HPV-related tumours might benefits all advantages from this surgical modality.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Primárias Desconhecidas / Infecções por Papillomavirus / Procedimentos Cirúrgicos Robóticos / Carcinoma de Células Escamosas de Cabeça e Pescoço / Neoplasias de Cabeça e Pescoço / Linfonodos Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Primárias Desconhecidas / Infecções por Papillomavirus / Procedimentos Cirúrgicos Robóticos / Carcinoma de Células Escamosas de Cabeça e Pescoço / Neoplasias de Cabeça e Pescoço / Linfonodos Idioma: En Ano de publicação: 2019 Tipo de documento: Article