Optimized Mucosal Modified Vaccinia Virus Ankara Prime/Soluble gp120 Boost HIV Vaccination Regimen Induces Antibody Responses Similar to Those of an Intramuscular Regimen.

Jones, Dorothy I; Pollara, Justin J; Johnson-Weaver, Brandi T; LaBranche, Celia C; Montefiori, David C; Pickup, David J; Permar, Sallie R; Abraham, Soman N; Maddaloni, Massimo; Pascual, David W; Staats, Herman F

Jones, Dorothy I; Pollara, Justin J; Johnson-Weaver, Brandi T; LaBranche, Celia C; Montefiori, David C; Pickup, David J; Permar, Sallie R; Abraham, Soman N; Maddaloni, Massimo; Pascual, David W; Staats, Herman F.

Afiliação

Jones DI; Department of Pathology, Duke University School of Medicine, Durham, North Carolina, USA.
Pollara JJ; Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA.
Johnson-Weaver BT; Department of Pathology, Duke University School of Medicine, Durham, North Carolina, USA.
LaBranche CC; Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA.
Montefiori DC; Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA.
Pickup DJ; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.
Permar SR; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.
Abraham SN; Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina, USA.
Maddaloni M; Department of Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Pascual DW; The Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Staats HF; Department of Pathology, Duke University School of Medicine, Durham, North Carolina, USA.

J Virol ; 93(14)2019 07 15.

Article em En | MEDLINE | ID: mdl-31068425

Assuntos

Vacinas contra a AIDS/imunologia; Anticorpos Anti-HIV/imunologia; Proteína gp120 do Envelope de HIV/imunologia; HIV-1/imunologia; Imunização Secundária; Vacinação; Vaccinia virus/imunologia; Vacinas contra a AIDS/genética; Administração Intranasal; Animais; Proteína gp120 do Envelope de HIV/genética; HIV-1/genética; Humanos; Imunidade nas Mucosas; Camundongos; Vaccinia virus/genética

Palavras-chave

HIV-1 vaccine; mucosal adjuvants; mucosal vaccines

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vaccinia virus / Anticorpos Anti-HIV / Proteína gp120 do Envelope de HIV / HIV-1 / Imunização Secundária / Vacinação / Vacinas contra a AIDS Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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