Phloretin loaded chitosan nanoparticles enhance the antioxidants and apoptotic mechanisms in DMBA induced experimental carcinogenesis.

Mariadoss, Arokia Vijaya Anand; Vinayagam, Ramachandran; Xu, Baojun; Venkatachalam, Karthikkumar; Sankaran, Vijayalakshmi; Vijayakumar, Shalini; Bakthavatsalam, Sandya Rani; A Mohamed, Sadiq; David, Ernest

Mariadoss, Arokia Vijaya Anand; Vinayagam, Ramachandran; Xu, Baojun; Venkatachalam, Karthikkumar; Sankaran, Vijayalakshmi; Vijayakumar, Shalini; Bakthavatsalam, Sandya Rani; A Mohamed, Sadiq; David, Ernest.

Afiliação

Mariadoss AVA; Department of Biotechnology, Thiruvalluvar University, Serkadu, Vellore, 632 115, Tamilnadu, India. Electronic address: mavijaibt@gmail.com.
Vinayagam R; Department of Biotechnology, Thiruvalluvar University, Serkadu, Vellore, 632 115, Tamilnadu, India.
Xu B; Food Science and Technology Program, Beijing Normal University-Hong Kong Baptist University, United International College, Zhuhai, 519087, China.
Venkatachalam K; Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates.
Sankaran V; Department of Biotechnology, Thiruvalluvar University, Serkadu, Vellore, 632 115, Tamilnadu, India.
Vijayakumar S; Department of Biotechnology, Thiruvalluvar University, Serkadu, Vellore, 632 115, Tamilnadu, India.
Bakthavatsalam SR; Center for Stem Cell Research, Christian Medical College, Vellore, 632004, India.
A Mohamed S; Adhiparasakthi College of Arts and Science, G.B. Nagar, Kalavai, 632 506, Tamilnadu, India.
David E; Department of Biotechnology, Thiruvalluvar University, Serkadu, Vellore, 632 115, Tamilnadu, India. Electronic address: ernestdavid2009@gmail.com.

Chem Biol Interact ; 308: 11-19, 2019 Aug 01.

Article em En | MEDLINE | ID: mdl-31071336

Assuntos

Antioxidantes/metabolismo; Apoptose/efeitos dos fármacos; Quitosana/química; Nanopartículas/química; Floretina/farmacologia; Administração Oral; Animais; Carcinoma de Células Escamosas/induzido quimicamente; Carcinoma de Células Escamosas/tratamento farmacológico; Carcinoma de Células Escamosas/patologia; Caspase 3/metabolismo; Cricetinae; Sistema Enzimático do Citocromo P-450/metabolismo; Citocromos c/metabolismo; Regulação para Baixo/efeitos dos fármacos; Peroxidação de Lipídeos/efeitos dos fármacos; Masculino; Neoplasias Bucais/induzido quimicamente; Neoplasias Bucais/tratamento farmacológico; Neoplasias Bucais/patologia; Floretina/química; Floretina/uso terapêutico; Proteínas Proto-Oncogênicas c-bcl-2/metabolismo; Proteína X Associada a bcl-2/metabolismo

Palavras-chave

Antioxidants; Chitosan nanoparticles; DMBA; Oral cancer; Phloretin

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Floretina / Apoptose / Quitosana / Nanopartículas / Antioxidantes Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google