Tissue-resident natural killer cells exacerbate tubulointerstitial fibrosis by activating transglutaminase 2 and syndecan-4 in a model of aristolochic acid-induced nephropathy.

Wee, Yu Mee; Go, Heounjeong; Choi, Monica Young; Jung, Hey Rim; Cho, Yong Mee; Kim, Young Hoon; Han, Duck Jong; Shin, Sung

Wee, Yu Mee; Go, Heounjeong; Choi, Monica Young; Jung, Hey Rim; Cho, Yong Mee; Kim, Young Hoon; Han, Duck Jong; Shin, Sung.

Afiliação

Wee YM; Department of Asan Institute for Life Science, Asan Medical Center, Seoul 05535, Korea.
Go H; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05535, Korea.
Choi MY; Department of Asan Institute for Life Science, Asan Medical Center, Seoul 05535, Korea.
Jung HR; Department of Asan Institute for Life Science, Asan Medical Center, Seoul 05535, Korea.
Cho YM; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05535, Korea.
Kim YH; Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05535, Korea.
Han DJ; Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05535, Korea.
Shin S; Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05535, Korea.

BMB Rep ; 52(9): 554-559, 2019 Sep.

Article em En | MEDLINE | ID: mdl-31072444

Assuntos

Ácidos Aristolóquicos/toxicidade; Proteínas de Ligação ao GTP/metabolismo; Nefropatias/metabolismo; Células Matadoras Naturais/metabolismo; Sindecana-4/metabolismo; Transglutaminases/metabolismo; Animais; Western Blotting; Modelos Animais de Doenças; Citometria de Fluxo; Rim/efeitos dos fármacos; Rim/metabolismo; Nefropatias/induzido quimicamente; Linfócitos/efeitos dos fármacos; Linfócitos/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Proteína 2 Glutamina gama-Glutamiltransferase; Baço/efeitos dos fármacos; Baço/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Transglutaminases / Proteínas de Ligação ao GTP / Ácidos Aristolóquicos / Sindecana-4 / Nefropatias Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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