Ubiquitin Signaling and Degradation of Aggregate-Prone Proteins.

Galves, Margarita; Rathi, Ritu; Prag, Gali; Ashkenazi, Avraham

Galves, Margarita; Rathi, Ritu; Prag, Gali; Ashkenazi, Avraham.

Afiliação

Galves M; Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Rathi R; School of Neurobiology, Biochemistry and Biophysics, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.
Prag G; School of Neurobiology, Biochemistry and Biophysics, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel. Electronic address: prag@tauex.tau.ac.il.
Ashkenazi A; Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel. Electronic address: ashkenaziavi@tauex.tau.ac.il.

Trends Biochem Sci ; 44(10): 872-884, 2019 10.

Article em En | MEDLINE | ID: mdl-31079890

Assuntos

Proteínas/metabolismo; Ubiquitina/metabolismo; Animais; Humanos; Modelos Moleculares; Agregados Proteicos; Proteínas/química; Proteínas/genética; Proteólise; Transdução de Sinais; Ubiquitina/química

Palavras-chave

E3 ubiquitin ligase; autophagy; deubiquitylating enzyme; neurodegenerative diseases; proteasome

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas / Ubiquitina Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas / Ubiquitina Idioma: En Ano de publicação: 2019 Tipo de documento: Article