Surgery on a dilated aorta associated with a connective tissue disease or inflammatory vasculitis in children and adolescents.
Cardiol Young
; 29(5): 564-569, 2019 May.
Article
em En
| MEDLINE
| ID: mdl-31111802
ABSTRACT
INTRODUCTION:
This research investigated patients who underwent surgery for a dilated aorta associated with a connective tissue disease or inflammatory vasculitis in children and adolescents. MATERIALS ANDMETHODS:
The medical records of 11 patients who underwent aortic surgery for dilatation resulting from a connective tissue disease or inflammatory vasculitis between 2000 and 2017 were retrospectively reviewed.RESULTS:
The median age and body weight of the patients were 9.6 years (range 5.4 months-15.5 years) and 25.8 kg (range 6.8-81.5), respectively. The associated diseases were Marfan syndrome (n = 3), Loeys-Dietz syndrome (n = 3), Kawasaki disease (n = 1), Takayasu arteritis (n = 1), PHACE syndrome (n = 1), tuberous sclerosis (n = 1), and unknown (n = 1). The most common initially affected area was the ascending aorta. During the 66.4 ± 35.9 months of follow-up, two Marfan syndrome patients died, and four patients (one Marfan syndrome and three Loeys-Dietz syndrome) had repeated aortic operation. Except for one patient, the functional class was well maintained in all patients who were followed up.CONCLUSION:
Cases of surgical treatment for a dilated aorta associated with a connective tissue disease and inflammatory vasculitis are rare in children and adolescents at our institution. Most of the patients in this study showed a tolerable postoperative course. However, the aorta showed progressive dilation over time even after surgical treatment, especially in patients with Loeys-Dietz syndrome. In these patients, close and more frequent regular follow-up is required.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Aorta Torácica
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Vasculite
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Doenças do Tecido Conjuntivo
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Dilatação Patológica
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article