Galectins-1 and -3 in Human Intervertebral Disc Degeneration: Non-Uniform Distribution Profiles and Activation of Disease Markers Involving NF-&#954;B by Galectin-1.

Elshamly, Mahmoud; Kinslechner, Katharina; Grohs, Josef G; Weinmann, Daniela; Walzer, Sonja M; Windhager, Reinhard; Gabius, Hans-Joachim; Toegel, Stefan

Galectins-1 and -3 in Human Intervertebral Disc Degeneration: Non-Uniform Distribution Profiles and Activation of Disease Markers Involving NF-κB by Galectin-1.

Elshamly, Mahmoud; Kinslechner, Katharina; Grohs, Josef G; Weinmann, Daniela; Walzer, Sonja M; Windhager, Reinhard; Gabius, Hans-Joachim; Toegel, Stefan.

Afiliação

Elshamly M; Department of Orthopedics and Trauma Surgery, Karl Chiari Lab for Orthopaedic Biology, Medical University of Vienna, 1090, Vienna, Austria.
Kinslechner K; Department of Orthopedics and Trauma Surgery, Division of Orthopedics, Medical University of Vienna, 1090, Vienna, Austria.
Grohs JG; Department of Orthopedics and Trauma Surgery, Karl Chiari Lab for Orthopaedic Biology, Medical University of Vienna, 1090, Vienna, Austria.
Weinmann D; Department of Orthopedics and Trauma Surgery, Division of Orthopedics, Medical University of Vienna, 1090, Vienna, Austria.
Walzer SM; Department of Orthopedics and Trauma Surgery, Karl Chiari Lab for Orthopaedic Biology, Medical University of Vienna, 1090, Vienna, Austria.
Windhager R; Department of Orthopedics and Trauma Surgery, Karl Chiari Lab for Orthopaedic Biology, Medical University of Vienna, 1090, Vienna, Austria.
Gabius HJ; Department of Orthopedics and Trauma Surgery, Karl Chiari Lab for Orthopaedic Biology, Medical University of Vienna, 1090, Vienna, Austria.
Toegel S; Department of Orthopedics and Trauma Surgery, Division of Orthopedics, Medical University of Vienna, 1090, Vienna, Austria.

J Orthop Res ; 37(10): 2204-2216, 2019 10.

Article em En | MEDLINE | ID: mdl-31115931

Assuntos

Galectina 1/metabolismo; Galectina 3/metabolismo; Degeneração do Disco Intervertebral/metabolismo; NF-kappa B/metabolismo; Adulto; Idoso; Biomarcadores/metabolismo; Feminino; Humanos; Masculino; Pessoa de Meia-Idade

Palavras-chave

anulus fibrosus; degeneration; lectin; notochord; nucleus pulposus

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Galectina 1 / Galectina 3 / Degeneração do Disco Intervertebral Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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