Labrenzbactin from a coral-associated bacterium Labrenzia sp.
J Antibiot (Tokyo)
; 72(8): 634-639, 2019 08.
Article
em En
| MEDLINE
| ID: mdl-31118481
ABSTRACT
A new catecholate-containing siderophore, labrenzbactin (1), was isolated from the fermentation broth of a coral-associated bacterium Labrenzia sp. The structure and absolute configuration of 1 was determined by spectroscopic methods and Marfey's analysis. Overall, 1 showed antimicrobial activity against Ralstonia solanacearum SUPP1541 and Micrococcus luteus ATCC9341 with MIC values of 25 and 50 µg ml-1, respectively, and cytotoxicity against P388 murine leukemia cells with an IC50 of 13 µM.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Oxazóis
/
Catecóis
/
Sideróforos
/
Alphaproteobacteria
/
Antozoários
/
Antibacterianos
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article