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A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
Sung, Yun Ju; de Las Fuentes, Lisa; Winkler, Thomas W; Chasman, Daniel I; Bentley, Amy R; Kraja, Aldi T; Ntalla, Ioanna; Warren, Helen R; Guo, Xiuqing; Schwander, Karen; Manning, Alisa K; Brown, Michael R; Aschard, Hugues; Feitosa, Mary F; Franceschini, Nora; Lu, Yingchang; Cheng, Ching-Yu; Sim, Xueling; Vojinovic, Dina; Marten, Jonathan; Musani, Solomon K; Kilpeläinen, Tuomas O; Richard, Melissa A; Aslibekyan, Stella; Bartz, Traci M; Dorajoo, Rajkumar; Li, Changwei; Liu, Yongmei; Rankinen, Tuomo; Smith, Albert Vernon; Tajuddin, Salman M; Tayo, Bamidele O; Zhao, Wei; Zhou, Yanhua; Matoba, Nana; Sofer, Tamar; Alver, Maris; Amini, Marzyeh; Boissel, Mathilde; Chai, Jin Fang; Chen, Xu; Divers, Jasmin; Gandin, Ilaria; Gao, Chuan; Giulianini, Franco; Goel, Anuj; Harris, Sarah E; Hartwig, Fernando P; He, Meian; Horimoto, Andrea R V R.
Afiliação
  • Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.
  • de Las Fuentes L; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.
  • Winkler TW; Cardiovascular Division, Department of Medicine, Washington University, St. Louis, MO, USA.
  • Chasman DI; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
  • Bentley AR; Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Kraja AT; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
  • Ntalla I; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
  • Warren HR; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Guo X; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Schwander K; NIHR Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, London, UK.
  • Manning AK; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
  • Brown MR; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.
  • Aschard H; Center for Human Genetics Research, Massachusetts General Hospital, Boston, MA, USA.
  • Feitosa MF; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Franceschini N; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Lu Y; Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
  • Cheng CY; Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Institut Pasteur, Paris, France.
  • Sim X; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
  • Vojinovic D; Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, USA.
  • Marten J; Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, NY, USA.
  • Musani SK; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
  • Kilpeläinen TO; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.
  • Richard MA; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Aslibekyan S; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore.
  • Bartz TM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Dorajoo R; Medical Research Council Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
  • Li C; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
  • Liu Y; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Rankinen T; Department of Environmental Medicine and Public Health, The Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Smith AV; Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Tajuddin SM; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Tayo BO; Cardiovascular Health Research Unit, Biostatistics and Medicine, University of Washington, Seattle, WA, USA.
  • Zhao W; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.
  • Zhou Y; Epidemiology and Biostatistics, University of Georgia at Athens College of Public Health, Athens, GA, USA.
  • Matoba N; Public Health Sciences, Epidemiology and Prevention, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
  • Sofer T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA.
  • Alver M; Icelandic Heart Association, Kopavogur, Iceland.
  • Amini M; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
  • Boissel M; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
  • Chai JF; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, USA.
  • Chen X; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
  • Divers J; Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • Gandin I; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Gao C; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Giulianini F; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.
  • Goel A; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.
  • Harris SE; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen RB, The Netherlands.
  • Hartwig FP; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France.
  • He M; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore.
  • Horimoto ARVR; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, Sweden.
Hum Mol Genet ; 28(15): 2615-2633, 2019 08 01.
Article em En | MEDLINE | ID: mdl-31127295
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Fumar / Grupos Raciais / Interação Gene-Ambiente / Pressão Arterial / Hipertensão Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Fumar / Grupos Raciais / Interação Gene-Ambiente / Pressão Arterial / Hipertensão Idioma: En Ano de publicação: 2019 Tipo de documento: Article