A new dimeric protoberberine alkaloid and other compounds from the tubers of Tinospora dentata.
Nat Prod Res
; 35(1): 17-24, 2021 Jan.
Article
em En
| MEDLINE
| ID: mdl-31135226
ABSTRACT
A new dimeric quaternary protoberberine alkaloid, bispalmatrubine (1), and thirteen known compounds (2-14) were purified from the tubers of Tinospora dentata. Their structures were determined by spectroscopic and spectrometric analytical methods. Among the isolates, eight compounds were examined for their in vitro anti-inflammatory potential and several tested alkaloids displayed moderate inhibitory effects of N-formyl-methionyl-leucyl-phenylalanine/cytochalasin B (fMLP/CB)-induced superoxide anion generation and elastase release.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Anti-Inflamatórios não Esteroides
/
Tinospora
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article