Switch from reference etanercept to SDZ ETN, an etanercept biosimilar, does not impact efficacy, safety, and immunogenicity of etanercept in patients with moderate-to-severe rheumatoid arthritis: 48-week results from the phase III, randomized, double-blind EQUIRA study.

Jaworski, Janusz; Matucci-Cerinic, Marco; Schulze-Koops, Hendrik; Buch, Maya H; Kucharz, Eugeniusz J; Allanore, Yannick; Kavanaugh, Arthur; Young, Philip; Babic, Goran

Jaworski, Janusz; Matucci-Cerinic, Marco; Schulze-Koops, Hendrik; Buch, Maya H; Kucharz, Eugeniusz J; Allanore, Yannick; Kavanaugh, Arthur; Young, Philip; Babic, Goran.

Afiliação

Jaworski J; Reumatika-Centrum Reumatologii, 02-691, Warsaw, Poland. januszjaworski@ymail.com.
Matucci-Cerinic M; Department of Experimental and Clinical Medicine, Division of Rheumatology AOUC, University of Florence, Florence, Italy.
Schulze-Koops H; Division of Rheumatology and Clinical Immunology, Department of Internal Medicine IV, Ludwig-Maximilians-University, Munich, Germany.
Buch MH; Leeds Institute of Rheumatic & Musculoskeletal Medicine, University of Leeds & NIHR Leeds Biomedical Research Centre, Leeds, UK.
Kucharz EJ; Department of Internal Medicine, Rheumatology and Clinical Immunology, Medical University of Silesia, Katowice, Poland.
Allanore Y; Cochin Hospital, Rheumatology A department, Paris Descartes University, Paris, France.
Kavanaugh A; UC San Diego School of Medicine, La Jolla, CA, USA.
Young P; Hexal AG, a Sandoz company, Holzkirchen, Germany.
Babic G; Hexal AG, a Sandoz company, Holzkirchen, Germany.

Arthritis Res Ther ; 21(1): 130, 2019 05 28.

Article em En | MEDLINE | ID: mdl-31138316

Assuntos

Antirreumáticos/uso terapêutico; Artrite Reumatoide/tratamento farmacológico; Medicamentos Biossimilares/uso terapêutico; Etanercepte/uso terapêutico; Adulto; Antirreumáticos/farmacocinética; Medicamentos Biossimilares/farmacocinética; Método Duplo-Cego; Substituição de Medicamentos; Etanercepte/farmacocinética; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Ensaios Clínicos Controlados Aleatórios como Assunto; Equivalência Terapêutica; Resultado do Tratamento

Palavras-chave

Biosimilar; Etanercept; Rheumatoid arthritis; SDZ ETN; Switch; Tumor necrosis factor inhibitor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Antirreumáticos / Medicamentos Biossimilares / Etanercepte Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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