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The functional observational battery and modified Irwin test as global neurobehavioral assessments in the rat: Pharmacological validation data and a comparison of methods.
Redfern, William S; Dymond, Angela; Strang, Isobel; Storey, Sharon; Grant, Claire; Marks, Louise; Barnard, Claire; Heys, Clive; Moyser, Katherine; Greenwood, Katherine; Cobey, Des; Moore, Nick; Karp, Natasha A; Prior, Helen.
Afiliação
  • Redfern WS; Global Safety Assessment, AstraZeneca, Alderley Park, Cheshire SK10 4TG, United Kingdom. Electronic address: will.redfern@certara.com.
  • Dymond A; Global Safety Assessment, AstraZeneca R&D Charnwood, Loughborough, Leicestershire LE11 5RH, United Kingdom.
  • Strang I; Global Safety Assessment, AstraZeneca, Alderley Park, Cheshire SK10 4TG, United Kingdom.
  • Storey S; Global Safety Assessment, AstraZeneca, Alderley Park, Cheshire SK10 4TG, United Kingdom.
  • Grant C; Global Safety Assessment, AstraZeneca, Alderley Park, Cheshire SK10 4TG, United Kingdom.
  • Marks L; Global Safety Assessment, AstraZeneca, Alderley Park, Cheshire SK10 4TG, United Kingdom.
  • Barnard C; Global Safety Assessment, AstraZeneca, Alderley Park, Cheshire SK10 4TG, United Kingdom.
  • Heys C; Global Safety Assessment, AstraZeneca, Alderley Park, Cheshire SK10 4TG, United Kingdom.
  • Moyser K; Global Safety Assessment, AstraZeneca, Alderley Park, Cheshire SK10 4TG, United Kingdom.
  • Greenwood K; Global Safety Assessment, AstraZeneca, Alderley Park, Cheshire SK10 4TG, United Kingdom.
  • Cobey D; Global Safety Assessment, AstraZeneca, Alderley Park, Cheshire SK10 4TG, United Kingdom.
  • Moore N; Global Safety Assessment, AstraZeneca, Alderley Park, Cheshire SK10 4TG, United Kingdom.
  • Karp NA; Data Sciences & Quantitative Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom.
  • Prior H; Global Safety Assessment, AstraZeneca, Alderley Park, Cheshire SK10 4TG, United Kingdom.
J Pharmacol Toxicol Methods ; 98: 106591, 2019.
Article em En | MEDLINE | ID: mdl-31146025
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Sistema Nervoso Central / Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Sistema Nervoso Central / Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos Idioma: En Ano de publicação: 2019 Tipo de documento: Article