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Lipidoid-siRNA Nanoparticle-Mediated IL-1ß Gene Silencing for Systemic Arthritis Therapy in a Mouse Model.
Song, Ping; Yang, Chuanxu; Thomsen, Jesper Skovhus; Dagnæs-Hansen, Frederik; Jakobsen, Maria; Brüel, Annemarie; Deleuran, Bent; Kjems, Jørgen.
Afiliação
  • Song P; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, 8000 Aarhus C, Denmark; Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark.
  • Yang C; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, 8000 Aarhus C, Denmark; Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark. Electronic address: chuanxuyang@inano.au.dk.
  • Thomsen JS; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
  • Dagnæs-Hansen F; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
  • Jakobsen M; Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark.
  • Brüel A; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
  • Deleuran B; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark; Department of Rheumatology, Aarhus University Hospital, 8000 Aarhus C, Denmark.
  • Kjems J; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, 8000 Aarhus C, Denmark; Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark. Electronic address: jk@mbg.au.dk.
Mol Ther ; 27(8): 1424-1435, 2019 08 07.
Article em En | MEDLINE | ID: mdl-31153827
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Terapia Genética / Técnicas de Transferência de Genes / Inativação Gênica / RNA Interferente Pequeno / Interleucina-1beta / Nanopartículas / Lipídeos Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Terapia Genética / Técnicas de Transferência de Genes / Inativação Gênica / RNA Interferente Pequeno / Interleucina-1beta / Nanopartículas / Lipídeos Idioma: En Ano de publicação: 2019 Tipo de documento: Article