Rapid chemical clearing of white matter in the post-mortem human brain by 1,2-hexanediol delipidation.

Inoue, Masafumi; Saito, Rie; Kakita, Akiyoshi; Tainaka, Kazuki

Inoue, Masafumi; Saito, Rie; Kakita, Akiyoshi; Tainaka, Kazuki.

Afiliação

Inoue M; Department of System Pathology for Neurological Disorders, Center for Bioresources, Brain Research Institute, Niigata University, 1-757 Asahimachidori, Chuo-ku, Niigata 951-8585, Japan.
Saito R; Department of Pathology, Brain Research Institute, Niigata University, 1-757 Asahimachidori, Chuo-ku, Niigata 951-8585, Japan.
Kakita A; Department of Pathology, Brain Research Institute, Niigata University, 1-757 Asahimachidori, Chuo-ku, Niigata 951-8585, Japan.
Tainaka K; Department of System Pathology for Neurological Disorders, Center for Bioresources, Brain Research Institute, Niigata University, 1-757 Asahimachidori, Chuo-ku, Niigata 951-8585, Japan. Electronic address: kztainaka@bri.niigata-u.ac.jp.

Bioorg Med Chem Lett ; 29(15): 1886-1890, 2019 08 01.

Article em En | MEDLINE | ID: mdl-31160178

Assuntos

Autopsia/métodos; Encéfalo/efeitos dos fármacos; Glicóis/uso terapêutico; Hexanos/uso terapêutico; Substância Branca/efeitos dos fármacos; Glicóis/farmacologia; Hexanos/farmacologia; Humanos

Palavras-chave

1,2-Hexanediol; Chemical tissue clearing; Delipidation; Neuropathology; White matter

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autopsia / Encéfalo / Substância Branca / Glicóis / Hexanos Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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