Ablation of All Synaptobrevin vSNAREs Blocks Evoked But Not Spontaneous Neurotransmitter Release at Neuromuscular Synapses.

Liu, Yun; Sugiura, Yoshie; Südhof, Thomas C; Lin, Weichun

Liu, Yun; Sugiura, Yoshie; Südhof, Thomas C; Lin, Weichun.

Afiliação

Liu Y; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, and.
Sugiura Y; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, and.
Südhof TC; Howard Hughes Medical Institute, Stanford University School of Medicine, Palo Alto, California 94304.
Lin W; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, and Weichun.Lin@UTSouthwestern.edu.

J Neurosci ; 39(31): 6049-6066, 2019 07 31.

Article em En | MEDLINE | ID: mdl-31160536

Assuntos

Junção Neuromuscular/metabolismo; Neurotransmissores/metabolismo; Proteínas R-SNARE/metabolismo; Transmissão Sináptica/fisiologia; Animais; Embrião de Mamíferos; Camundongos; Camundongos Knockout; Neurogênese/fisiologia; Junção Neuromuscular/embriologia; Sinapses

Palavras-chave

KO mice; evoked release; neuromuscular junction; spontaneous release; synapse formation; synaptic transmission

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transmissão Sináptica / Neurotransmissores / Proteínas R-SNARE / Junção Neuromuscular Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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