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A unique combination adjuvant modulates immune responses preventing vaccine-enhanced pulmonary histopathology after a single dose vaccination with fusion protein and challenge with respiratory syncytial virus.
Lee, Youri; Ko, Eun-Ju; Kim, Ki-Hye; Lee, Young-Tae; Hwang, Hye Suk; Kwon, Young-Man; Graham, Barney S; Kang, Sang Moo.
Afiliação
  • Lee Y; Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA.
  • Ko EJ; Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA; Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Kim KH; Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA.
  • Lee YT; Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA.
  • Hwang HS; Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA; Department of Microbiology, Chonnam National University Medical School, Hwasun-gun, Jeonnam, 58128, South Korea.
  • Kwon YM; Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA.
  • Graham BS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Kang SM; Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA. Electronic address: skang24@gsu.edu.
Virology ; 534: 1-13, 2019 08.
Article em En | MEDLINE | ID: mdl-31163351
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Virais de Fusão / Adjuvantes Imunológicos / Vírus Sincicial Respiratório Humano / Infecções por Vírus Respiratório Sincicial / Vacinas contra Vírus Sincicial Respiratório / Pulmão Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Virais de Fusão / Adjuvantes Imunológicos / Vírus Sincicial Respiratório Humano / Infecções por Vírus Respiratório Sincicial / Vacinas contra Vírus Sincicial Respiratório / Pulmão Idioma: En Ano de publicação: 2019 Tipo de documento: Article