Long-term effects of surgical treatment on baroreflex function in patients with obstructive sleep apnea: an 18-month follow-up.
Sleep Med
; 60: 152-158, 2019 08.
Article
em En
| MEDLINE
| ID: mdl-31175049
ABSTRACT
OBJECTIVE:
Depressed baroreflex sensitivity (BRS) is reported in obstructive sleep apnea (OSA). Improvement of BRS short-term after surgical treatment is also reported. We tested the hypothesis that surgical treatment not only improves clinical outcomes, but also improves BRS after 18 months.METHODS:
Cardiovascular autonomic tests, polysomnography (PSG), and biochemical testing were prospectively evaluated in 54 OSA patients at three time points (preoperatively, 6 months and 18 months postoperatively) and compared with 20, age- and body mass index (BMI)-matched, healthy controls.RESULTS:
The BRS increased after surgical treatment at 18-month follow-up, with results similar to the healthy control. Additionally, average O2, mO2 <90% (% per night), and lowest O2 showed an increase after surgical treatment at the 18-month follow-up.CONCLUSIONS:
Besides improvement in clinical outcomes, depressed BRS in OSA patients is reversible and these patients have the potential for total recovery of baroreflex function after 18 months of treatment.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sistema Nervoso Autônomo
/
Barorreflexo
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Apneia Obstrutiva do Sono
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article