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Changes in Bone Mass After Discontinuation of Preexposure Prophylaxis With Tenofovir Disoproxil Fumarate/Emtricitabine in Young Men Who Have Sex With Men: Extension Phase Results of Adolescent Trials Network Protocols 110 and 113.
Havens, Peter L; Perumean-Chaney, Suzanne E; Patki, Amit; Cofield, Stacey S; Wilson, Craig M; Liu, Nancy; Anderson, Peter L; Landovitz, Raphael J; Kapogiannis, Bill G; Hosek, Sybil G; Mulligan, Kathleen.
Afiliação
  • Havens PL; Department of Pediatrics, Medical College of Wisconsin/Children's Hospital of Wisconsin, Milwaukee.
  • Perumean-Chaney SE; Department of Biostatistics, University of Alabama at Birmingham.
  • Patki A; Department of Biostatistics, University of Alabama at Birmingham.
  • Cofield SS; Department of Biostatistics, University of Alabama at Birmingham.
  • Wilson CM; Department of Epidemiology, University of Alabama at Birmingham.
  • Liu N; Westat, Rockville, Maryland.
  • Anderson PL; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora.
  • Landovitz RJ; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles.
  • Kapogiannis BG; Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.
  • Hosek SG; Department of Psychiatry, Stroger Hospital of Cook County, Chicago, Illinois.
  • Mulligan K; Department of Medicine, University of California at San Francisco, Zuckerberg San Francisco General Hospital.
Clin Infect Dis ; 70(4): 687-691, 2020 02 03.
Article em En | MEDLINE | ID: mdl-31179503
ABSTRACT
Human immunodeficiency virus-seronegative men aged 15-22 years who lost bone mineral density (BMD) during tenofovir disoproxil fumarate/emtricitabine preexposure prophylaxis (PrEP) showed BMD recovery 48 weeks following PrEP discontinuation. Lumbar spine and whole body BMD z-scores remained below baseline 48 weeks off PrEP in participants aged 15-19 years. Clinical Trials Registration. NCT01772823 (ATN 110) and NCT01769456 (ATN 113).
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Fármacos Anti-HIV / Profilaxia Pré-Exposição / Minorias Sexuais e de Gênero Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Fármacos Anti-HIV / Profilaxia Pré-Exposição / Minorias Sexuais e de Gênero Idioma: En Ano de publicação: 2020 Tipo de documento: Article