Changes in Bone Mass After Discontinuation of Preexposure Prophylaxis With Tenofovir Disoproxil Fumarate/Emtricitabine in Young Men Who Have Sex With Men: Extension Phase Results of Adolescent Trials Network Protocols 110 and 113.
Clin Infect Dis
; 70(4): 687-691, 2020 02 03.
Article
em En
| MEDLINE
| ID: mdl-31179503
ABSTRACT
Human immunodeficiency virus-seronegative men aged 15-22 years who lost bone mineral density (BMD) during tenofovir disoproxil fumarate/emtricitabine preexposure prophylaxis (PrEP) showed BMD recovery 48 weeks following PrEP discontinuation. Lumbar spine and whole body BMD z-scores remained below baseline 48 weeks off PrEP in participants aged 15-19 years. Clinical Trials Registration. NCT01772823 (ATN 110) and NCT01769456 (ATN 113).
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MEDLINE
Assunto principal:
Infecções por HIV
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Fármacos Anti-HIV
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Profilaxia Pré-Exposição
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Minorias Sexuais e de Gênero
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article