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Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells.
Kampen, Kim R; Fancello, Laura; Girardi, Tiziana; Rinaldi, Gianmarco; Planque, Mélanie; Sulima, Sergey O; Loayza-Puch, Fabricio; Verbelen, Benno; Vereecke, Stijn; Verbeeck, Jelle; Op de Beeck, Joyce; Royaert, Jonathan; Vermeersch, Pieter; Cassiman, David; Cools, Jan; Agami, Reuven; Fiers, Mark; Fendt, Sarah-Maria; De Keersmaecker, Kim.
Afiliação
  • Kampen KR; Laboratory for Disease Mechanisms in Cancer, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium.
  • Fancello L; Laboratory for Disease Mechanisms in Cancer, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium.
  • Girardi T; Laboratory for Disease Mechanisms in Cancer, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium.
  • Rinaldi G; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, 3000, Leuven, Belgium.
  • Planque M; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium.
  • Sulima SO; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, 3000, Leuven, Belgium.
  • Loayza-Puch F; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium.
  • Verbelen B; Laboratory for Disease Mechanisms in Cancer, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium.
  • Vereecke S; Translational Control and Metabolism, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Verbeeck J; Laboratory for Disease Mechanisms in Cancer, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium.
  • Op de Beeck J; Laboratory for Disease Mechanisms in Cancer, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium.
  • Royaert J; Laboratory for Disease Mechanisms in Cancer, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium.
  • Vermeersch P; Laboratory for Disease Mechanisms in Cancer, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium.
  • Cassiman D; Laboratory for Disease Mechanisms in Cancer, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium.
  • Cools J; Department of Laboratory Medicine, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Agami R; Department of Gastroenterology-Hepatology and Metabolic Center, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Fiers M; Laboratory of Molecular Biology of Leukemia, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, 3000, Leuven, Belgium.
  • Fendt SM; Laboratory of Molecular Biology of Leukemia, Center for Human Genetics, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium.
  • De Keersmaecker K; Department of Pediatric Oncology/Hematology, Erasmus Medical Center, Wytemaweg 80, 3015 CN, Rotterdam, the Netherlands.
Nat Commun ; 10(1): 2542, 2019 06 11.
Article em En | MEDLINE | ID: mdl-31186416
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Serina / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Glicina / Mutação Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Serina / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Glicina / Mutação Idioma: En Ano de publicação: 2019 Tipo de documento: Article