A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea.

Prajapati-DiNubila, Meenakshi; Benito-Gonzalez, Ana; Golden, Erin Jennifer; Zhang, Shuran; Doetzlhofer, Angelika

Prajapati-DiNubila, Meenakshi; Benito-Gonzalez, Ana; Golden, Erin Jennifer; Zhang, Shuran; Doetzlhofer, Angelika.

Afiliação

Prajapati-DiNubila M; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, United States.
Benito-Gonzalez A; Center for Sensory Biology, Johns Hopkins University School of Medicine, Baltimore, United States.
Golden EJ; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, United States.
Zhang S; Center for Sensory Biology, Johns Hopkins University School of Medicine, Baltimore, United States.
Doetzlhofer A; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, United States.

Elife ; 82019 06 12.

Article em En | MEDLINE | ID: mdl-31187730

Assuntos

Ativinas/metabolismo; Diferenciação Celular; Cóclea/citologia; Folistatina/metabolismo; Células Ciliadas Auditivas/citologia; Animais; Ciclo Celular; Células Ciliadas Auditivas/metabolismo; Camundongos; Transdução de Sinais

Palavras-chave

activin signaling; auditory cell differentiation; cochlea; developmental biology; follistatin; hair cell; inner ear; mouse; neuroscience

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Cóclea / Ativinas / Folistatina / Células Ciliadas Auditivas Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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