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Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase.
Brown, Ariane J; Won, John J; Graham, Rachel L; Dinnon, Kenneth H; Sims, Amy C; Feng, Joy Y; Cihlar, Tomas; Denison, Mark R; Baric, Ralph S; Sheahan, Timothy P.
Afiliação
  • Brown AJ; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Won JJ; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Graham RL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Dinnon KH; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Sims AC; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Feng JY; Gilead Sciences, Inc., Foster City, CA, USA.
  • Cihlar T; Gilead Sciences, Inc., Foster City, CA, USA.
  • Denison MR; Department of Pediatrics-Infectious Diseases, Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Sheahan TP; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: sheahan@email.unc.edu.
Antiviral Res ; 169: 104541, 2019 09.
Article em En | MEDLINE | ID: mdl-31233808
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / RNA Polimerase Dependente de RNA / Monofosfato de Adenosina / Coronavirus Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / RNA Polimerase Dependente de RNA / Monofosfato de Adenosina / Coronavirus Idioma: En Ano de publicação: 2019 Tipo de documento: Article