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Safety, efficacy and tumor mutational burden as a biomarker of overall survival benefit in chemo-refractory gastric cancer treated with toripalimab, a PD-1 antibody in phase Ib/II clinical trial NCT02915432.
Wang, F; Wei, X L; Wang, F H; Xu, N; Shen, L; Dai, G H; Yuan, X L; Chen, Y; Yang, S J; Shi, J H; Hu, X C; Lin, X Y; Zhang, Q Y; Feng, J F; Ba, Y; Liu, Y P; Li, W; Shu, Y Q; Jiang, Y; Li, Q; Wang, J W; Wu, H; Feng, H; Yao, S; Xu, R H.
Afiliação
  • Wang F; State Key Laboratory of Oncology in South China, Department of Medical Oncology, Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou.
  • Wei XL; State Key Laboratory of Oncology in South China, Department of Medical Oncology, Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou.
  • Wang FH; State Key Laboratory of Oncology in South China, Department of Medical Oncology, Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou.
  • Xu N; Department of Medical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou.
  • Shen L; Laboratory of Carcinogenesis & Translational Research for the Ministry of National Education, Department of GI Oncology, Peking University School of Oncology, Beijing Cancer Hospital & Institute, Beijing.
  • Dai GH; Department of Medical Oncology, Chinese PLA General Hospital & Chinese PLA Medical Academy, Beijing.
  • Yuan XL; Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan.
  • Chen Y; The State Key Laboratory of Biotherapy, Department of Abdominal Cancer, West China Medical School, Cancer Center, West China Hospital, Sichuan University, Chengdu.
  • Yang SJ; Department of Internal Medicine, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou.
  • Shi JH; Department of Medical Oncology, Linyi Cancer Hospital, Linyi.
  • Hu XC; Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai.
  • Lin XY; Department of Medical Oncology, Fujian Medical University Union Hospital, Fuzhou.
  • Zhang QY; Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin.
  • Feng JF; Department of Oncology, Nanjing Medical University Affiliated Cancer Hospital, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing.
  • Ba Y; Department of Gastrointestinal Oncology, Tianjin Cancer Hospital, Tianjin.
  • Liu YP; Department of Medical Oncology, The First Hospital of China Medical University, Shenyang.
  • Li W; Department of Medical Oncology, The First Hospital of Jilin University, Changchun.
  • Shu YQ; Department of Oncology, Jiangsu Provincial Hospital, Nanjing.
  • Jiang Y; Digestive Medical Oncology, Cancer Hospital of Shantou University Medical College, Shantou.
  • Li Q; Department of Medical Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai.
  • Wang JW; State Key Laboratory of Oncology in South China, Department of Ultrasonography, Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou.
  • Wu H; Shanghai Junshi Biosciences Co., Ltd, Shanghai, China.
  • Feng H; Shanghai Junshi Biosciences Co., Ltd, Shanghai, China.
  • Yao S; Shanghai Junshi Biosciences Co., Ltd, Shanghai, China.
  • Xu RH; State Key Laboratory of Oncology in South China, Department of Medical Oncology, Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou. Electronic address: xurh@sysucc.org.cn.
Ann Oncol ; 30(9): 1479-1486, 2019 09 01.
Article em En | MEDLINE | ID: mdl-31236579
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Anticorpos Monoclonais Humanizados / Antineoplásicos Imunológicos / Anticorpos Monoclonais Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Anticorpos Monoclonais Humanizados / Antineoplásicos Imunológicos / Anticorpos Monoclonais Idioma: En Ano de publicação: 2019 Tipo de documento: Article