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Selectively Biodegradable Polyesters: Nature-Inspired Construction Materials for Future Biomedical Applications.
Urbánek, Tomás; Jäger, Eliézer; Jäger, Alessandro; Hrubý, Martin.
Afiliação
  • Urbánek T; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského námestí 2, 162 00 Prague 6, Czech Republic. urbanekto@gmail.com.
  • Jäger E; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského námestí 2, 162 00 Prague 6, Czech Republic. jager@imc.cas.cz.
  • Jäger A; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského námestí 2, 162 00 Prague 6, Czech Republic. ajager@imc.cas.cz.
  • Hrubý M; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského námestí 2, 162 00 Prague 6, Czech Republic. mhruby@centrum.cz.
Polymers (Basel) ; 11(6)2019 Jun 19.
Article em En | MEDLINE | ID: mdl-31248100
ABSTRACT
In the last half-century, the development of biodegradable polyesters for biomedical applications has advanced significantly. Biodegradable polyester materials containing external stimuli-sensitive linkages are favored in the development of therapeutic devices for pharmacological applications such as delivery vehicles for controlled/sustained drug release. These selectively biodegradable polyesters degrade after particular external stimulus (e.g., pH or redox potential change or the presence of certain enzymes). This review outlines the current development of biodegradable synthetic polyesters materials able to undergo hydrolytic or enzymatic degradation for various biomedical applications, including tissue engineering, temporary implants, wound healing and drug delivery.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article