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HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure.
Firulli, Beth A; George, Rajani M; Harkin, Jade; Toolan, Kevin P; Gao, Hongyu; Liu, Yunlong; Zhang, Wenjun; Field, Loren J; Liu, Ying; Shou, Weinian; Payne, Ronald Mark; Rubart-von der Lohe, Michael; Firulli, Anthony B.
Afiliação
  • Firulli BA; Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut St, Indianapolis, IN 46202-5225, USA.
  • George RM; Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut St, Indianapolis, IN 46202-5225, USA.
  • Harkin J; Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut St, Indianapolis, IN 46202-5225, USA.
  • Toolan KP; Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut St, Indianapolis, IN 46202-5225, USA.
  • Gao H; Department of and Medical and Molecular Genetics, Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, 975 West Walnut Street, Indianapolis, IN 46202-5225, USA.
  • Liu Y; Department of and Medical and Molecular Genetics, Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, 975 West Walnut Street, Indianapolis, IN 46202-5225, USA.
  • Zhang W; Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut St, Indianapolis, IN 46202-5225, USA.
  • Field LJ; Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut St, Indianapolis, IN 46202-5225, USA.
  • Liu Y; Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut St, Indianapolis, IN 46202-5225, USA.
  • Shou W; Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut St, Indianapolis, IN 46202-5225, USA.
  • Payne RM; Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut St, Indianapolis, IN 46202-5225, USA.
  • Rubart-von der Lohe M; Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut St, Indianapolis, IN 46202-5225, USA.
  • Firulli AB; Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut St, Indianapolis, IN 46202-5225, USA.
Cardiovasc Res ; 116(3): 605-618, 2020 03 01.
Article em En | MEDLINE | ID: mdl-31286141
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição Hélice-Alça-Hélice Básicos / Coração / Cardiopatias Congênitas / Insuficiência Cardíaca / Miocárdio Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição Hélice-Alça-Hélice Básicos / Coração / Cardiopatias Congênitas / Insuficiência Cardíaca / Miocárdio Idioma: En Ano de publicação: 2020 Tipo de documento: Article