Metabolomic Profiling of Body Fluids in Mouse Models Demonstrates that Nuclear Magnetic Resonance Is a Putative Diagnostic Tool for the Presence of Thyroid Hormone Receptor &#945;1 Mutations.

Boumaza, Houda; Markossian, Suzy; Busi, Baptiste; Rautureau, Gilles J P; Gauthier, Karine; Elena-Herrmann, Bénédicte; Flamant, Frédéric

Metabolomic Profiling of Body Fluids in Mouse Models Demonstrates that Nuclear Magnetic Resonance Is a Putative Diagnostic Tool for the Presence of Thyroid Hormone Receptor α1 Mutations.

Boumaza, Houda; Markossian, Suzy; Busi, Baptiste; Rautureau, Gilles J P; Gauthier, Karine; Elena-Herrmann, Bénédicte; Flamant, Frédéric.

Afiliação

Boumaza H; Institut des Sciences Analytiques, UMR 5280, CNRS, ENS de Lyon, Université Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France.
Markossian S; Institut de Génomique Fonctionnelle de Lyon, INRA USC 1370, Université de Lyon, Université Lyon 1, CNRS UMR 5242, Ecole Normale Supérieure de Lyon, Lyon, France.
Busi B; Institut de Génomique Fonctionnelle de Lyon, INRA USC 1370, Université de Lyon, Université Lyon 1, CNRS UMR 5242, Ecole Normale Supérieure de Lyon, Lyon, France.
Rautureau GJP; Institut des Sciences Analytiques, UMR 5280, CNRS, ENS de Lyon, Université Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France.
Gauthier K; Institut des Sciences Analytiques, UMR 5280, CNRS, ENS de Lyon, Université Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France.
Elena-Herrmann B; Institut de Génomique Fonctionnelle de Lyon, INRA USC 1370, Université de Lyon, Université Lyon 1, CNRS UMR 5242, Ecole Normale Supérieure de Lyon, Lyon, France.
Flamant F; Institut des Sciences Analytiques, UMR 5280, CNRS, ENS de Lyon, Université Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France.

Thyroid ; 29(9): 1327-1335, 2019 09.

Article em En | MEDLINE | ID: mdl-31298651

Assuntos

Líquidos Corporais/metabolismo; Espectroscopia de Ressonância Magnética/métodos; Metabolômica/métodos; Mutação; Receptores alfa dos Hormônios Tireóideos/genética; Animais; Genes erbA; Humanos; Hipotireoidismo/genética; Masculino; Camundongos; Camundongos Endogâmicos C57BL

Palavras-chave

metabolomics; mouse models; nuclear magnetic resonance; rare disease; resistance to thyroid hormone α; thyroid hormone receptor

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Líquidos Corporais / Espectroscopia de Ressonância Magnética / Receptores alfa dos Hormônios Tireóideos / Metabolômica / Mutação Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google