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Structural development of a type-1 ryanodine receptor (RyR1) Ca2+-release channel inhibitor guided by endoplasmic reticulum Ca2+ assay.
Mori, Shuichi; Iinuma, Hiroto; Manaka, Noriaki; Ishigami-Yuasa, Mari; Murayama, Takashi; Nishijima, Yoshiaki; Sakurai, Akiko; Arai, Ryota; Kurebayashi, Nagomi; Sakurai, Takashi; Kagechika, Hiroyuki.
Afiliação
  • Mori S; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, 101-0062, Japan.
  • Iinuma H; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, 101-0062, Japan.
  • Manaka N; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, 101-0062, Japan.
  • Ishigami-Yuasa M; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, 101-0062, Japan.
  • Murayama T; Department of Cellular and Molecular Pharmacology, Juntendo University Graduate School of Medicine, Tokyo, 113-8421, Japan.
  • Nishijima Y; Department of Cellular and Molecular Pharmacology, Juntendo University Graduate School of Medicine, Tokyo, 113-8421, Japan.
  • Sakurai A; Department of Cellular and Molecular Pharmacology, Juntendo University Graduate School of Medicine, Tokyo, 113-8421, Japan.
  • Arai R; Department of Cellular and Molecular Pharmacology, Juntendo University Graduate School of Medicine, Tokyo, 113-8421, Japan.
  • Kurebayashi N; Department of Cellular and Molecular Pharmacology, Juntendo University Graduate School of Medicine, Tokyo, 113-8421, Japan.
  • Sakurai T; Department of Cellular and Molecular Pharmacology, Juntendo University Graduate School of Medicine, Tokyo, 113-8421, Japan.
  • Kagechika H; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, 101-0062, Japan. Electronic address: kage.chem@tmd.ac.jp.
Eur J Med Chem ; 179: 837-848, 2019 Oct 01.
Article em En | MEDLINE | ID: mdl-31299492
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cálcio / Quinolonas / Canal de Liberação de Cálcio do Receptor de Rianodina / Retículo Endoplasmático Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cálcio / Quinolonas / Canal de Liberação de Cálcio do Receptor de Rianodina / Retículo Endoplasmático Idioma: En Ano de publicação: 2019 Tipo de documento: Article