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Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as inverse agonists of the CB1 receptor - SAR efforts towards selectivity and peripheralization.
Amato, George; Wiethe, Robert; Manke, Amruta; Vasukuttan, Vineetha; Snyder, Rodney; Runyon, Scott; Maitra, Rangan.
Afiliação
  • Amato G; Discovery Science and Technology, RTI International, 3040 Cornwallis Rd., Research Triangle Park, NC 27709-2194, USA.
  • Wiethe R; Discovery Science and Technology, RTI International, 3040 Cornwallis Rd., Research Triangle Park, NC 27709-2194, USA.
  • Manke A; Discovery Science and Technology, RTI International, 3040 Cornwallis Rd., Research Triangle Park, NC 27709-2194, USA.
  • Vasukuttan V; Discovery Science and Technology, RTI International, 3040 Cornwallis Rd., Research Triangle Park, NC 27709-2194, USA.
  • Snyder R; Discovery Science and Technology, RTI International, 3040 Cornwallis Rd., Research Triangle Park, NC 27709-2194, USA.
  • Runyon S; Discovery Science and Technology, RTI International, 3040 Cornwallis Rd., Research Triangle Park, NC 27709-2194, USA.
  • Maitra R; Discovery Science and Technology, RTI International, 3040 Cornwallis Rd., Research Triangle Park, NC 27709-2194, USA. Electronic address: rmaitra@rti.org.
Bioorg Med Chem ; 27(16): 3632-3649, 2019 08 15.
Article em En | MEDLINE | ID: mdl-31301950
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Purinas / Receptor CB1 de Canabinoide Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Purinas / Receptor CB1 de Canabinoide Idioma: En Ano de publicação: 2019 Tipo de documento: Article