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Effect of 12-week home-based cognitive training on cognitive function and brain metabolism in patients with amnestic mild cognitive impairment.
Park, Jinse; Kim, Si-Eun; Kim, Eun-Joo; Lee, Byung In; Jeong, Jee Hyang; Na, Hae Ri; Choi, Seong Hye; Kang, Do-Young; Park, Kyung Won.
Afiliação
  • Park J; Department of Neurology, Haueundae Paik Hospital, Inje University, Busan, South Korea.
  • Kim SE; Department of Neurology, Haueundae Paik Hospital, Inje University, Busan, South Korea.
  • Kim EJ; Department of Neurology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Busan, South Korea.
  • Lee BI; Department of Neurology, Haueundae Paik Hospital, Inje University, Busan, South Korea.
  • Jeong JH; Department of Neurology, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, South Korea.
  • Na HR; Department of Neurology, Bobath Memorial Hospital, Seongnam, South Korea.
  • Choi SH; Department of Neurology, Inha University School of Medicine, Incheon, South Korea.
  • Kang DY; Department of Nuclear Medicine, College of Medicine, Dong-A University, Busan, South Korea.
  • Park KW; Department of Neurology, Cognitive Disorders and Dementia Center, Dong-A University College of Medicine and Institute of Convergence Bio-Health, Busan, South Korea.
Clin Interv Aging ; 14: 1167-1175, 2019.
Article em En | MEDLINE | ID: mdl-31303750
ABSTRACT

PURPOSE:

We assessed the effect of home-based cognitive intervention (HCI) on cognitive function along with brain metabolism by 18F-FDG PET in patients with amnestic MCI (aMCI). PATIENTS AND

METHODS:

Fifty-seven patients with aMCI from three hospitals were randomized (30 HCI, 27 control). For 12 weeks, subjects received HCI. Thirty-two subjects (15 HCI, 17 control) underwent brain 18-F-FDG-PET imaging at baseline and at 12 and 24 weeks.

RESULTS:

The HCI group showed significant improvement in the scores of the Controlled Oral Word Association Test (COWAT) 12 and at 24 weeks. Significant brain metabolic changes by 18F-FDG PET were not observed.

CONCLUSION:

The current study suggests that HCI was effective in improving general cognition along with frontal executive function in patients with aMCI.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terapia Cognitivo-Comportamental / Cognição / Disfunção Cognitiva Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terapia Cognitivo-Comportamental / Cognição / Disfunção Cognitiva Idioma: En Ano de publicação: 2019 Tipo de documento: Article