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Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles.
Yuen, Tsz Ying; Brown, Christopher J; Xue, Yuezhen; Tan, Yaw Sing; Ferrer Gago, Fernando J; Lee, Xue Er; Neo, Jin Yong; Thean, Dawn; Kaan, Hung Yi Kristal; Partridge, Anthony W; Verma, Chandra S; Lane, David P; Johannes, Charles W.
Afiliação
  • Yuen TY; Institute of Chemical and Engineering Sciences , Agency for Science , Technology and Research , 8 Biomedical Grove, Neuros, #07-01 , Singapore 138665 . Email: yuenty@ices.a-star.edu.sg.
  • Brown CJ; P53 Laboratory , Agency for Science , Technology and Research , 8A Biomedical Grove, #06-06, Immunos , Singapore 138648.
  • Xue Y; P53 Laboratory , Agency for Science , Technology and Research , 8A Biomedical Grove, #06-06, Immunos , Singapore 138648.
  • Tan YS; Bioinformatics Institute , Agency for Science , Technology and Research , 30 Biopolis Street, #07-01, Matrix , Singapore 138671.
  • Ferrer Gago FJ; P53 Laboratory , Agency for Science , Technology and Research , 8A Biomedical Grove, #06-06, Immunos , Singapore 138648.
  • Lee XE; P53 Laboratory , Agency for Science , Technology and Research , 8A Biomedical Grove, #06-06, Immunos , Singapore 138648.
  • Neo JY; Institute of Chemical and Engineering Sciences , Agency for Science , Technology and Research , 8 Biomedical Grove, Neuros, #07-01 , Singapore 138665 . Email: yuenty@ices.a-star.edu.sg.
  • Thean D; P53 Laboratory , Agency for Science , Technology and Research , 8A Biomedical Grove, #06-06, Immunos , Singapore 138648.
  • Kaan HYK; MSD Translational Medicine Research Centre , 8 Biomedical Grove #04-01, Neuros , Singapore 138665.
  • Partridge AW; MSD Translational Medicine Research Centre , 8 Biomedical Grove #04-01, Neuros , Singapore 138665.
  • Verma CS; Bioinformatics Institute , Agency for Science , Technology and Research , 30 Biopolis Street, #07-01, Matrix , Singapore 138671.
  • Lane DP; P53 Laboratory , Agency for Science , Technology and Research , 8A Biomedical Grove, #06-06, Immunos , Singapore 138648.
  • Johannes CW; Institute of Chemical and Engineering Sciences , Agency for Science , Technology and Research , 8 Biomedical Grove, Neuros, #07-01 , Singapore 138665 . Email: yuenty@ices.a-star.edu.sg.
Chem Sci ; 10(26): 6457-6466, 2019 Jul 14.
Article em En | MEDLINE | ID: mdl-31316744

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article