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Genome Analysis of A Novel South African Cydia pomonella granulovirus (CpGV-SA) with Resistance-Breaking Potential.
Motsoeneng, Boitumelo; Jukes, Michael D; Knox, Caroline M; Hill, Martin P; Moore, Sean D.
Afiliação
  • Motsoeneng B; Department of Biochemistry and Microbiology, Rhodes University, P.O. Box 94, Grahamstown 6140, South Africa.
  • Jukes MD; Department of Biochemistry and Microbiology, Rhodes University, P.O. Box 94, Grahamstown 6140, South Africa. mrmdjukes@gmail.com.
  • Knox CM; Centre for Biological Control, Department of Zoology and Entomology, Rhodes University, P.O. Box 94, Grahamstown 6140, South Africa. mrmdjukes@gmail.com.
  • Hill MP; Department of Biochemistry and Microbiology, Rhodes University, P.O. Box 94, Grahamstown 6140, South Africa.
  • Moore SD; Centre for Biological Control, Department of Zoology and Entomology, Rhodes University, P.O. Box 94, Grahamstown 6140, South Africa.
Viruses ; 11(7)2019 07 18.
Article em En | MEDLINE | ID: mdl-31323859
The complete genome of an endemic South African Cydia pomonella granulovirus isolate was sequenced and analyzed. Several missing or truncated open reading frames (ORFs) were identified, including a 24 bp deletion in the pe38 gene which is reported to be associated with type I resistance-breaking potential. Comparison of single nucleotide polymorphisms (SNPs) with five other fully sequenced CpGV isolates identified 67 unique events, 47 of which occurred within ORFs, leading to several amino acid changes. Further analysis of single nucleotide variations (SNVs) within CpGV-SA revealed that this isolate consists of mixed genotypes. Phylogenetic analysis using complete genome sequences placed CpGV-SA basal to M, I12 and E2 and distal to S and I07 but with no distinct classification into any of the previously defined CpGV genogroups. These results suggest that CpGV-SA is a novel and genetically distinct isolate with significant potential as a biopesticide for management of codling moth (CM), not only in South Africa, but potentially in other pome fruit producing countries, particularly where CM resistance to CpGV has been reported.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma Viral / Genômica / Granulovirus / Interações Hospedeiro-Patógeno / Mariposas Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma Viral / Genômica / Granulovirus / Interações Hospedeiro-Patógeno / Mariposas Idioma: En Ano de publicação: 2019 Tipo de documento: Article