Elevated HOX gene expression in acute myeloid leukemia is associated with NPM1 mutations and poor survival.
J Adv Res
; 20: 105-116, 2019 Nov.
Article
em En
| MEDLINE
| ID: mdl-31333881
AML, acute myeloid leukemia; Acute myeloid leukemia; Clinical samples; FAB classification, FrenchAmericanBritish classification; FC, fold change; Gene expression; HOX genes; HOX, homeobox; HR, hazard ratio; ITD, internal tandem duplication; MEIS, myeloid ecotropic viral integration site; Mutation; NCBI GEO, National Center for Biotechnology Gene expression Omnibus; OS, overall survival; PBX, pre-B-cell leukemia homeobox; Survival; TCGA, The Cancer Genome Atlas; WHO, World Health Organization; qPCR, quantitative polymerase chain reaction
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2019
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