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Survival and specific outcome of sickle cell disease patients after renal transplantation.
Gérardin, Christel; Moktefi, Anissa; Couchoud, Cécile; Duquesne, Alyette; Ouali, Nacera; Gataut, Philippe; Karras, Alexandre; Anglicheau, Dany; Lefaucheur, Carmen; Figueres, Lucile; Albano, Laetitia; Lionet, Arnaud; Novion, Marine; Ziliotis, Marie-Julia; Louis, Magali; Del Bello, Arnaud; Matignon, Marie; Dahan, Karine; Habibi, Anoosha; Galacteros, Frederic; Bartolucci, Pablo; Grimbert, Philippe; Audard, Vincent.
Afiliação
  • Gérardin C; AP-HP (Assistance Publique-Hôpitaux de Paris), Department of Nephrology and Transplantation, Rare French Disease Centre "Idiopathic Nephrotic syndrome", Henri-Mondor/Albert-Chenevier Hospital, Créteil, France.
  • Moktefi A; Inserm U955, Team 21, DHU VIC, Paris-Est University, Créteil, France.
  • Couchoud C; Inserm U955, Team 21, DHU VIC, Paris-Est University, Créteil, France.
  • Duquesne A; AP-HP, Department of Pathology, Henri-Mondor/Albert-Chenevier Hospital, Créteil, France.
  • Ouali N; REIN registry. Agence de la Biomédecine, Saint Denis La Plaine, France.
  • Gataut P; Department of Nephrology, André Grégoire Hospital, Montreuil, France.
  • Karras A; AP-HP, Department of Nephrology and Transplantation, Tenon Hospital, Sorbonne University, Paris, France.
  • Anglicheau D; Department of Nephrology, Hypertension, Transplantation and Dialysis Bretonneau Hospital, Centre Hospitalo Universitaire (CHU) Tours, Tours, France.
  • Lefaucheur C; AP-HP, Department of Nephrology, Européen Gorges Pompidou Hospital, Paris, France.
  • Figueres L; AP-HP, Department of Nephrology and Kidney Transplantation, Necker Hospital, Paris, France.
  • Albano L; Descartes University, Réseau Thématique de Recherche et de Soins Centaure, LabEx Transplantex, Paris, France.
  • Lionet A; AP-HP, Department of Nephrology and Transplantation, Saint-Louis Hospital, Paris, France.
  • Novion M; Institute of Transplantation Urology and Nephrology (ITUN), CHU Nantes, Nantes University, Nantes, France.
  • Ziliotis MJ; Department of Nephrology, Dialysis, and Renal Transplantation, CHU Nice, Nice, France.
  • Louis M; Department of Nephrology, Transplantation and Dialysis, Huriez University Hospital, Lille, France.
  • Del Bello A; Department of Nephrology, Transplantation, Dialysis and Apheresis, Pellegrin University Hospital, Bordeaux, France.
  • Matignon M; Department of Nephrology, Dialysis, and Renal Transplantation, CHU Besançon, Besançon, France.
  • Dahan K; Transplant Federation, François Mitterrand University Hospital, CHU Dijon, Dijon, France.
  • Habibi A; Department of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France.
  • Galacteros F; AP-HP (Assistance Publique-Hôpitaux de Paris), Department of Nephrology and Transplantation, Rare French Disease Centre "Idiopathic Nephrotic syndrome", Henri-Mondor/Albert-Chenevier Hospital, Créteil, France.
  • Bartolucci P; Inserm U955, Team 21, DHU VIC, Paris-Est University, Créteil, France.
  • Grimbert P; AP-HP, Department of Nephrology and Dialysis, Tenon Hospital, Sorbonne University, Paris, France.
  • Audard V; AP-HP, Sickle Cell Referral Centre, Henri-Mondor/Albert-Chenevier Hospital, Créteil, France.
Br J Haematol ; 187(5): 676-680, 2019 12.
Article em En | MEDLINE | ID: mdl-31348518
The prognosis of sickle cell disease (SCD) patients who need dialysis is poor, but experience with kidney transplantation is limited. This study assessed the characteristics of 36 SCD patients undergoing renal transplantation. Immediate post-surgical complications occurred in 25% of cases. Cytomegalovirus and bacterial infections were frequently observed. Twelve patients died after a median follow-up period of 17·4 months. Overall patient survival was significantly lower in SCD than in the control group without significant difference for overall death-censored graft survival. Our data suggest that renal transplantation should be systematically considered in SCD patients with end-stage renal disease.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transplante de Rim / Anemia Falciforme / Falência Renal Crônica Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transplante de Rim / Anemia Falciforme / Falência Renal Crônica Idioma: En Ano de publicação: 2019 Tipo de documento: Article