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NYX-2925 induces metabotropic N-methyl-d-aspartate receptor (NMDAR) signaling that enhances synaptic NMDAR and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor.
Bowers, M Scott; Cacheaux, Luisa P; Sahu, Srishti U; Schmidt, Mary E; Sennello, Joseph A; Leaderbrand, Katherine; Khan, M Amin; Kroes, Roger A; Moskal, Joseph R.
Afiliação
  • Bowers MS; Falk Center for Molecular Therapeutics, Biomedical Engineering, Northwestern University, Evanston, Illinois, USA.
  • Cacheaux LP; Aptinyx, Inc., Evanston, Illinois, USA.
  • Sahu SU; Aptinyx, Inc., Evanston, Illinois, USA.
  • Schmidt ME; Falk Center for Molecular Therapeutics, Biomedical Engineering, Northwestern University, Evanston, Illinois, USA.
  • Sennello JA; Aptinyx, Inc., Evanston, Illinois, USA.
  • Leaderbrand K; Aptinyx, Inc., Evanston, Illinois, USA.
  • Khan MA; Aptinyx, Inc., Evanston, Illinois, USA.
  • Kroes RA; Aptinyx, Inc., Evanston, Illinois, USA.
  • Moskal JR; Falk Center for Molecular Therapeutics, Biomedical Engineering, Northwestern University, Evanston, Illinois, USA.
J Neurochem ; 152(5): 523-541, 2020 03.
Article em En | MEDLINE | ID: mdl-31376158
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Espiro / Sinapses / Receptores de N-Metil-D-Aspartato / Receptores de AMPA Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Espiro / Sinapses / Receptores de N-Metil-D-Aspartato / Receptores de AMPA Idioma: En Ano de publicação: 2020 Tipo de documento: Article