Vemurafenib may overcome TNF-related apoptosis-inducing ligand (TRAIL) resistance in anaplastic thyroid cancer cells.

Pilli, Tania; Cantara, Silvia; Marzocchi, Carlotta; Pacini, Furio; Prabhakar, Bellur S; Castagna, Maria Grazia

Pilli, Tania; Cantara, Silvia; Marzocchi, Carlotta; Pacini, Furio; Prabhakar, Bellur S; Castagna, Maria Grazia.

Afiliação

Pilli T; Department of Medical and Surgical Sciences and Neurosciences, University of Siena, Siena, Italy.
Cantara S; Department of Medical and Surgical Sciences and Neurosciences, University of Siena, Siena, Italy.
Marzocchi C; Department of Medical and Surgical Sciences and Neurosciences, University of Siena, Siena, Italy.
Pacini F; Department of Medical and Surgical Sciences and Neurosciences, University of Siena, Siena, Italy.
Prabhakar BS; Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, IL, USA.
Castagna MG; Department of Medical and Surgical Sciences and Neurosciences, University of Siena, Siena, Italy. m.g.castagna@ao-siena.toscana.it.

Endocrine ; 67(1): 117-123, 2020 01.

Article em En | MEDLINE | ID: mdl-31377969

Assuntos

Carcinoma Anaplásico da Tireoide; Neoplasias da Glândula Tireoide; Animais; Apoptose; Linhagem Celular Tumoral; Camundongos; Ligante Indutor de Apoptose Relacionado a TNF; Carcinoma Anaplásico da Tireoide/tratamento farmacológico; Neoplasias da Glândula Tireoide/tratamento farmacológico; Vemurafenib/farmacologia; Vemurafenib/uso terapêutico

Palavras-chave

Anaplastic thyroid cancer; Apoptosis; Kinase inhibitors; TRAIL

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Glândula Tireoide / Carcinoma Anaplásico da Tireoide Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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