Methanolic extract of Mitragyna speciosa Korth leaf inhibits ethanol seeking behaviour in mice: involvement of antidopaminergic mechanism.

Vijeepallam, Kamini; Pandy, Vijayapandi; Murugan, Dharmani Devi; Naidu, Murali

Vijeepallam, Kamini; Pandy, Vijayapandi; Murugan, Dharmani Devi; Naidu, Murali.

Afiliação

Vijeepallam K; Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Pandy V; Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. pandiphd@gmail.com.
Murugan DD; Department of Pharmacology, Chalapathi Institute of Pharmaceutical Sciences, Chalapathi Nagar, Lam, Guntur, Andhra Pradesh, 522034, India. pandiphd@gmail.com.
Naidu M; Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.

Metab Brain Dis ; 34(6): 1713-1722, 2019 12.

Article em En | MEDLINE | ID: mdl-31396844

Assuntos

Dopamina/metabolismo; Comportamento de Procura de Droga/efeitos dos fármacos; Etanol/administração & dosagem; Núcleo Accumbens/efeitos dos fármacos; Extratos Vegetais/farmacologia; Recompensa; Animais; Condicionamento Operante/efeitos dos fármacos; Masculino; Camundongos; Mitragyna; Núcleo Accumbens/metabolismo; Folhas de Planta; Autoadministração

Palavras-chave

Alcohol dependence; Antidopaminergic; Conditioned place preference; Mitragyna speciosa; Nucleus accumbens; Runway model of drug self-administration

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Recompensa / Extratos Vegetais / Dopamina / Etanol / Comportamento de Procura de Droga / Núcleo Accumbens Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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